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Extreme sensitivity biosensing platform based on hyperbolic metamaterials.
- K. Sreekanth, Y. Alapan, +5 authors G. Strangi
- Medicine, Materials Science
- Nature materials
- 1 June 2016
Optical sensor technology offers significant opportunities in the field of medical research and clinical diagnostics, particularly for the detection of small numbers of molecules in highly diluted… Expand
Heterogeneous Red Blood Cell Adhesion and Deformability in Sickle Cell Disease
We present a microfluidic approach that allows simultaneous interrogation of RBC properties in physiological flow conditions at a single cell level. With this method, we studied healthy hemoglobin A… Expand
Application of Hydrogels in Ocular Tissue Engineering
Vipuil Kishore***, Yunus Alapan, Ranjani Iyer, Ryan Mclay* and Umut A. Gurkan║ Department of Chemical Engineering, Florida Institute of Technology, Melbourne, FL 32901, USA Department of Biomedical… Expand
Soft erythrocyte-based bacterial microswimmers for cargo delivery
Erythrocyte-based microswimmers offer superior efficiency, stability, and deformability for active and guided cargo delivery. Bacteria-propelled biohybrid microswimmers have recently shown to be able… Expand
Dynamic deformability of sickle red blood cells in microphysiological flow.
In sickle cell disease (SCD), hemoglobin molecules polymerize intracellularly and lead to a cascade of events resulting in decreased deformability and increased adhesion of red blood cells (RBCs).… Expand
Sickle cell disease biochip: a functional red blood cell adhesion assay for monitoring sickle cell disease.
- Y. Alapan, Ceonne Kim, +4 authors U. Gurkan
- Medicine, Biology
- Translational research : the journal of…
- 1 July 2016
Sickle cell disease (SCD) afflicts millions of people worldwide and is associated with considerable morbidity and mortality. Chronic and acute vaso-occlusion are the clinical hallmarks of SCD and can… Expand
Three-Dimensional Printing Based Hybrid Manufacturing of Microfluidic Devices.
- Y. Alapan, M. N. Hasan, Richang Shen, U. Gurkan
- Materials Science, Medicine
- Journal of nanotechnology in engineering and…
- 1 May 2015
Microfluidic platforms offer revolutionary and practical solutions to challenging problems in biology and medicine. Even though traditional micro/nanofabrication technologies expedited the emergence… Expand
Emerging point-of-care technologies for sickle cell disease screening and monitoring
ABSTRACT Introduction: Sickle Cell Disease (SCD) affects 100,000 Americans and more than 14 million people globally, mostly in economically disadvantaged populations, and requires early diagnosis… Expand
A multiband perfect absorber based on hyperbolic metamaterials
- K. Sreekanth, M. ElKabbash, Y. Alapan, A. R. Rashed, U. Gurkan, G. Strangi
- Physics, Medicine
- Scientific reports
- 18 May 2016
In recent years, considerable research efforts have been focused on near-perfect and perfect light absorption using metamaterials spanning frequency ranges from microwaves to visible frequencies.… Expand
Microalga-Powered Microswimmers toward Active Cargo Delivery.
- O. Yasa, Pelin Erkoc, Y. Alapan, M. Sitti
- Materials Science, Medicine
- Advanced materials
- 1 November 2018
Nature presents intriguing biological swimmers with innate energy harvesting abilities from their local environments. Use of natural swimmers as cargo delivery agents presents an alternative strategy… Expand