Y. Y. He

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Focal adhesion kinase (FAK) is an important mediator of extracellular matrix integrin signaling, cell motility, cell proliferation and cell survival. Increased FAK expression is observed in a variety of solid human tumors and increased FAK expression and activity frequently correlate with metastatic disease and poor prognosis. Herein we identify miR-7 as a(More)
Negative differential resistance ͑NDR͒ is reported for a bilayer molecular junction. The system is comprised of a Hg–alkanethiol//arenethiol–Au bilayer molecular junction formed by bringing into contact a tetradecanethiol self-assembled monolayer ͑SAM͒-coated drop of Hg with the surface of an oligo͑phenylene-ethynylene͒ SAM on Au. Persistent, reproducible(More)
MicroRNAs play an important role in the regulation of cancer migration, invasion and metastasis. Patients with triple-negative breast cancer (TNBC) have a high incidence of early relapse and metastasis; however, the molecular basis for metastasis and recurrence in these individuals remains largely unknown. Herein, we demonstrate that miR-136 is an(More)
The p38 mitogen-activated protein kinase (MAPK) identified in human monocytes represents a potentially attractive therapeutic target for a class of cytokine suppressive anti-inflammatory compounds. However, the limitations of protein therapeutics have stimulated significant research aimed at developing orally bioavailable, small molecular inhibitors of(More)
Highly ordered Fe-MCM-41 molecular sieve was successfully synthesized by using n-hexadecyl-trimethyl ammonium bromide (CTAB) as the template and the iron ore tailings (IOTs) as the silicon and iron source. X-ray diffraction (XRD), high-resolution transmission electron microscopy (HRTEM), diffuse reflectance UV-visible spectroscopy, (29)Si magic-angle(More)
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