Y-Y Chu

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Placental villus tissue obtained from pregnant women of 6 to 7 weeks was cultured in vitro for four days, with or without addition of tamoxifen (Tam), an antiestrogenic drug. The levels of both progesterone (P) and human chorionic gonadotropin (hCG) in culture medium collected every day were measured by using radio-immuno assay, so as to observe the effects(More)
Ipalbidine (Ipa) is a photoactive alkaloid isolated from the seeds of ipomoea hardwickki Hemsl. The analgesic effects of Ipa were determined by rat tail flick method. A dose-dependent analgesic effect was found after s.c. or i.c.v. administration of Ipa, but no analgesia was observed after intrathecal injection, indicating that the analgesic effect of Ipa(More)
In the present study, the antipregnancy effect of (D-Ala6, Pro9-Ethylamide10) LHRH (LHRH-A) on midgestation rats was observed. The results indicate that LHRH-A could terminate pregnancy of all experimented rats by abortion after subcutaneous administration of 200 micrograms LHRH-A (dissolved in vegetable oil) once a day at days 9 to 11 of their pregnancy.(More)
  • J Li, Y H Chu
  • 1990
Guinea pig trachea strips were isolated after 21 d of ovalbumin-sensitization. Challenging the preparations with antigen induced a double-phase contractile response (DPCR) which consisted of a rapid contraction (RC) and a tonic contraction (TC). The effects of tetrodotoxin (TTX), atropine, hexamethonium, diphenhydramine and a substance P (SP) antagonist on(More)
OBJECTIVE To study the excretion of urinary proteins in women at different periods of pregnancy and women with pregnancy induced hypertension. METHODS Urinary proteins (albumin, IgA, IgG, IgM) were measured at random with enzyme-linked immunosorbent assay (ELISA) in 101 normal pregnant women, 25 women with pregnancy induced hypertension and 28 nonpregnant(More)
It is known that luteinizing hormone-releasing hormone (LHRH) and its agonistic analogs could act directly on various extrapituitary target tissues by activating their specific receptors present in these tissues. In this report, we proposed an in vitro assay method for testing the bioactivities of LHRH agonists based on their inhibitory effect on human(More)