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In recent years, a lot of efforts have been made in conformational epitope prediction as antigen proteins usually bind antibodies with an assembly of sequentially discontinuous and structurally compact surface residues. Currently, only a few methods for spatial epitope prediction are available with focus on single residue propensity scales or continual(More)
Spatio-temporal dynamics associated with a class of coupled membrane-bulk PDE-ODE models in one spatial dimension is analyzed using a combination of linear stability theory, numerical bifurcation software, and full time-dependent simulations. In our simplified 1-D setting, the mathematical model consists of two dynamically active membranes, separated(More)
We report the results of a genome-wide scan conducted in 219 individuals from 34 large multiplex nuclear pedigrees from the northern Han Chinese population at an average resolution of about 10 cM. Nonparametric two-point and multipoint linkage analyses were performed to detect evidence of linkage with type 2 diabetes in this study. On chromosome 1 four(More)
A high-reflectivity omni directional reflector (ODR) has been incorporated into a GaInN lightemitting diode (LED) structure. The ODR comprises a transparent, electrically conductive quarterwave layer of indium tin oxide clad by silver and serves as an ohmic contact to p-type GaN. It is shown that ODR-LEDs have low optical losses and high extraction(More)
Three mutants of the wild type α-amylase gene from Xanthomonas campestris pv. campestris 8004 were obtained using a PCR technique in which deoxythymidine triphosphate (dTTP) was partially replaced by 5-bromo-2′-deoxyuridine-5′-triphosphate (BrdUTP), at an optimal dTTP:BrdUTP ratio of 1000:1. Of thre three mutants that were obtained and which were sequenced,(More)
The objective of the present study was to investigate the in vivo pharmacokinetics of huperzine A in healthy human volunteers. Twelve subjects (M 6, F 6; age ranged from 20 ∼ 25 years) participated in the study. Huperzine A was administered in tablet form at a single dose of 0.4 mg. Following oral administration, the presence of huperzine A started to(More)
The dynamic expression of genes for oil and protein contents of rapeseed (Brassica napus L.) was carried out with time-dependent measures by using the developmental genetic models for quantitative traits in diploid plant. The unconditional and conditional analysis showed that the accumulated genetic effects or net genetic effects from diploid embryo nuclear(More)
Temperature dependence of electroluminescence (EL) efficiency in blue InGaN-GaN multiple-quantum-well (MQW) light-emitting diodes (LEDs) with different well widths is systematically investigated. The EL efficiency at 300 K shows a maximum at the input current of 4, 10, and 60 mA for the LEDs with 1.5-, 2.0-, and 2.5-nm QWs, respectively. Nevertheless, the(More)
A zinc oxide (ZnO) nanorod based surface acoustic wave (SAW) sensor has been developed and investigated towards hydrogen (H2) gas. The ZnO nanorods were deposited onto a layered ZnO/64° YX LiNbO3 substrate using a liquid solution method. Micro-characterization results revealed that the diameters of ZnO nanorods are around 100 and 40 nm on LiNbO3 and Au(More)
This paper proposes an embedded ultra low power nonvolatile memory in a standard CMOS logic process. The memory adopts a bit cell based on the differential floating gate PMOS structure and a novel operating scheme. It can greatly improve the endurance and retention characteristic and make the area/bit smaller. A new high efficiency all-PMOS charge pump is(More)