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The release of enzymes from the acrosome of the sperm head (acrosome reaction) starts the fertilization process and enables the spermatozoa to penetrate the zona pellucida of the oocytes. Defective acrosome reaction is one of the important causes of infertility in men. To investigate the molecular regulation of spermatogenesis in vivo, we used differential(More)
Immunoglobulin heavy chain (IGH) gene-associated translocations occur frequently in different subtypes of B-cell lymphomas. These translocations result in deregulated expression of partner genes and play pivotal roles in the pathogenesis of lymphomas. Molecular characterization of IGH-associated translocation breakpoints has been instrumental in the(More)
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