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Forty buffaloes naturally infected with Trypanosoma evansi in the South of China were treated with a single dose of a new arsenical. Cymelarsan (Mel Cy) at 0.25 mg/kg to 3.0 mg/kg by intramuscular injection. All animals were cured, with the exception of two out of four animals treated with 0.25 mg/kg Mel Cy which relapsed two months after drug(More)
Lung overstretch involves mechanical factors, including large tidal volumes (VT), which induce inflammatory responses. The current authors hypothesised that inspiratory flow contributes to ventilator-induced inflammation. Buffer-perfused rabbit lungs were ventilated for 2 h with 21%, O2+5%, CO2, positive end-expiratory pressure of 2-3 cmH2O and randomly(More)
Gram negative sepsis causes changes in oxygen supply-demand relationships. We have used a primate model of hyperdynamic gram negative sepsis produced by intravenous infusion of Escherichia coli (E. coli) to evaluate sepsis-induced alterations in mitochondrial oxidation-reduction (redox) state in muscle in vivo. The redox state of cytochrome a,a3, the(More)
An important unanswered question about clinical use of pancreas transplantation is: can pancreas transplants reverse or, at least, stabilize well-established lesions of insulin-dependent diabetes mellitus (IDDM)? To answer this question, we performed whole pancreas transplantations in 190 highly inbred rats 6, 9, 12, 15, 18, and 21 mo after induction of(More)
Venous malformations (VMs) are the most common vascular developmental anomalies (birth defects) . These defects are caused by developmental arrest of the venous system during various stages of embryogenesis. VMs remain a difficult diagnostic and therapeutic challenge due to the wide range of clinical presentations, unpredictable clinical course, erratic(More)
In situ hybridization with biotinylated DNA viral probes (ISH-B) for human papillomavirus (HPV) types 6/11, 16, 18, 31, and 33 was used to study the outcome in 32 cases of mild and 21 cases of moderate cervical dysplasia with koilocytotic change that were followed for an average of 27 mo. The rates of regression, persistence, and progression for cervical(More)
8 cases of duodenal villous tumor were reported. A total of 11 tumors, with 2 in the bulb and 9 in the descending part, were excised. Malignant change was found in 4 cases (50%). Diagnosis could be made by using hypotonic duodenography and fibroscopy. The integral tumor should be examined by frozen section during operation, so as to determining the(More)