Y. -T. Hsu

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Benzyl isothiocyanate (BITC) is a cruciferous vegetable-derived compound with anticancer properties in human cancer cells. However, its anticancer potential and underlying mechanisms remain absent in human oral cancer cells. Results indicate that BITC inhibits growth, promotes G2/M phase arrest and triggers apoptosis of OC2 cells with a minimal toxicity to(More)
Apoptosis is a highly complex form of cell death that can be triggered by alterations in Ca2+ homeostasis. Members of the Bcl-2 family may regulate apoptosis and modulate Ca2+ distribution within intracellular compartments. Bax, a proapoptotic member of the family, is constitutively expressed and soluble in the cytosol and, under apoptotic induction,(More)
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