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Hepatitis B virus surface antigen (HBsAg) plays an important role in maintaining the tolerance and may interfere with host innate and adaptive immune responses; therefore, novel therapeutic strategies to reduce HBsAg loads in patients infected with hepatitis B virus (HBV) are emerging as an attractive but challenging issue. Metformin could regulate hepatic(More)
Is visitors’ attendance a fair indicator of a web site’s quality? Internet sub-domains are usually characterized by power law distributions of visits, thus suggesting a richer-get-richer process. If this is the case, the number of visits is not a relevant measure of quality. If, on the other hand, there are active players, i.e. visitors who can tell the(More)
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