Learn More
BACKGROUND Dopamine D4 receptor (DRD4) gene polymorphisms are associated with various pharmacologic activities. This study investigated whether polymorphisms of 48-bp tandem repeats in the exon 3 of the DRD4 gene are related to neuroleptic response. METHODS The neuroleptic response at the acute stage of schizophrenia was assessed in 80 (48 men, 32 women)(More)
Using an adenoviral system as a delivery mediator of therapeutic gene, we investigated the therapeutic effects of the use of combined MDR1 shRNA and human NIS (hNIS) radioiodine gene therapy in a mouse colon xenograft model. In vitro uptake of Tc-99m sestamibi was increased approximately two-fold in cells infected with an adenovirus vector that expressed(More)
Low molecular weight GTP-binding proteins are molecular switches that are believed to play pivotal roles in cell growth, differentiation, cytoskeletal organization, and vesicular trafficking. Rab proteins are key players in the regulation of vesicular transport, while Rho family members control actin-dependent cell functions, i.e. the regulation of(More)
Editorial New year's greetings M. Mizuguchi (Japan) 1 Review Article Pacemaker in complicated and refractory breath-holding spells: When to think about it? Original Articles Manifestation of both emetic seizures and sylvian seizures in the same patients with benign partial epilepsy 18 Efficacy and tolerability of high-dose prednisone in Chinese children(More)
  • 1