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Anti‐histone H1 IgGs from blood serum of systemic lupus erythematosus patients are capable of hydrolyzing histone H1 and myelin basic protein
Novel hydrolytic activity of the anti‐histone H1 antibodies (Ab) toward histone H1 and myelin basic protein (MBP) was shown. Blood serum of ten patients with clinically diagnosed systemic lupusExpand
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Blood serum immunoglobulins of patients with multiple myeloma are capable of hydrolysing histone H1.
BACKGROUND Recently we have shown that the imunoglobulins G from blood serum of some multiple sclerosis patients are capable of cleaving histone H1. AIM To check whether histone H1-hydrolyzingExpand
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Desialylation of dying cells with catalytically active antibodies possessing sialidase activity facilitate their clearance by human macrophages
Recently we reported the first known incidence of antibodies possessing catalytic sialidase activity (sialidase abzymes) in the serum of patients with multiple myeloma and systemic lupusExpand
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Two-step chromatography purification of IgGs possessing sialidase activity from human blood serum.
Sialation of cell surface is known to be tightly connected with tumorigenicity, invasiveness, metastatic potential and clearance of aged cells, while sialation of immunoglobulin G (IgG) moleculesExpand
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