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OBJECTIVE To assess effects of quality of life (QOL), spirituality, and religiosity on rate of progression of cognitive decline in Alzheimer disease (AD). METHODS In this longitudinal study, we recruited 70 patients with probable AD. The Mini-Mental State Examination was used to monitor the rate of cognitive decline. Religiosity and spirituality were(More)
In associative agnosia early perceptual processing of faces or objects are considered to be intact, while the ability to access stored semantic information about the individual face or object is impaired. Recent claims, however, have asserted that associative agnosia is also characterized by deficits at the perceptual level, which are too subtle to be(More)
Parkinson's disease (PD) manifestations include motor symptoms and behavioural deficits that resemble schizophrenia negative symptoms. The N-methyl-D-aspartate subtype of glutamate receptor (NMDAR) represents a novel pharmacological target in PD. D-serine (DSR) allosterically modulates in-vivo NMDAR-mediated neurotransmission and has been shown to improve(More)
1 University of Cincinnati College of Medicine, Cincinnati, OH, United States, 2 Department of Neurology, James J and Joan A. Gardner Center for Parkinson’s Disease and Movement Disorders, University of Cincinnati, Cincinnati, OH, United States, 3 Tikvah for Parkinson, Jerusalem, Israel, 4 Departments of Internal Medicine and Neurology, Massachusetts(More)
A literature review of spirituality in coping with early-stage Alzheimer's disease. [From the abstract:] …The purpose of this literature review is to examine the existing body of knowledge about spirituality in coping with Alzheimer's disease and to apply a spiritual framework of coping in organizing the literature to identify themes and gaps in knowledge.(More)
Sirs: Normal pressure hydrocephalus (NPH) is characterized by progressive gait disorder, cognitive decline and sphincteric incontinence that develop in association with ventriculomegaly and normal CSF opening pressure, and improve following CSF drainage [8]. Cognitive impairments in NPH consist of confusion, psychomotor slowing, executive dysfunction and(More)
Alzheimer's disease is characterized by progressive cognitive and functional decline. Recently, there have been reports in the medical literature on artists who continued to paint while suffering from Alzheimer's. This article describes the changes that occurred in the work of three artists who suffered from Alzheimer's: William Utermohlen, Carolus Horn and(More)
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