Y -I Nabeshima

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Hyperthermia is thought to be a teratogen in many animal species and also in humans. It has been reported that hyperthermia caused by sauna, hot tub, or fever during the early stages of pregnancy is related to an increased risk for neural tube defects. During exercise, especially in hot conditions, body temperature can also rise to fairly high levels. Thus,(More)
It is well established that prolactin release during exercise is one of the important factors in exercise-induced menstrual dysfunction. The purpose of this study is to clarify the mechanisms of prolactin release during exercise. Ten female athletes measured their BBT every morning. They performed incremental exercise on a cycle ergometer, with or without(More)
Klotho, a transmembrane protein with anti-aging properties, regulates phosphate, calcium and bone metabolism, induces resistance against oxidative stress and may participate in insulin signalling. Neonates, especially preterm ones, are prone to metabolic disturbances and oxidative stress.Objective: To evaluate circulating Klotho concentrations in preterm(More)
In athletic women menstrual disorders such as luteal insufficiency, oligomenorrhea and amenorrhea are often seen. It has been suggested that such disorders may be related to hypothalamic-pituitary axis insufficiency caused by physical activity. To investigate the mechanism by which the disorder is promoted, episodic gonadotropin secretion was studied in 10(More)
Fetal physiology during swimming in pregnancy has remained unclear. To assess the fetal status, the fetal heart rate (FHR) was measured during maternal swimming. We studied individually a group of seventeen women in normal pregnancy (during their third trimester, 35-38th week) who participated in a maternal swimming class. We adapted the Doppler ultra-sound(More)
The effect of maternal exercise on the fetal and maternal heart rate was studied in 10 normal pregnant women in their third trimester. They participated in 15 minute graded treadmill exercise. Fetal heart rate (FHR), uterine contraction, maternal blood pressure, electrocardiogram, and oxygen consumption were monitored, before, during, and after exercise.(More)
OBJECTIVE To determine the effect of maternal exercise on the fetal blood flow of normal and growth-retarded fetuses. METHODS The effect of maternal exercise on fetal blood flow was investigated with 24 pregnant women between 36 and 42 weeks' gestation. Seventeen pregnancies were uncomplicated (normal group) and the other 7 were complicated with(More)
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