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  • Esa Tahvanainen, M Syvanne, +7 authors Christian Ehnholm
  • Medicine
  • The Journal of clinical investigation
  • 1998 (First Publication: 1 March 1998)
  • The associations between six genetic polymorphisms in the hepatic lipase (HL) gene (LIPC) and variation in postheparin HL activity and fasting serum lipoproteins were evaluated in 395 male FinnishContinue Reading
  • Y Antero Kesaniemi, Joseph L Witztum, Urs P. Steinbrecher
  • Chemistry, Medicine
  • The Journal of clinical investigation
  • 1983 (First Publication: 1 April 1983)
  • Low density lipoprotein (LDL) catabolism occurs by LDL receptor-dependent and LDL receptor-independent pathways. We have shown previously that nonenzymatic glucosylation of LDL in the presence ofContinue Reading
  • Joseph L Witztum, Urs P. Steinbrecher, Y Antero Kesaniemi, Martin A. Fisher
  • Chemistry, Medicine
  • Proceedings of the National Academy of Sciences…
  • 1984 (First Publication: 1 May 1984)
  • Nonenzymatic glucosylation interferes with recognition of low density lipoprotein (LDL) by its receptor and markedly decreases the rate of plasma clearance of glucosylated LDL, both in experimentalContinue Reading
  • Urs P. Steinbrecher, Joseph L Witztum, Y Antero Kesaniemi, R L Elam
  • Chemistry, Medicine
  • The Journal of clinical investigation
  • 1983 (First Publication: 1 April 1983)
  • We previously showed that glucosylation of lysine residues of low density lipoproteins (LDL) blocks high-affinity degradation by cultured human fibroblasts, and markedly slows LDL turnover in guineaContinue Reading