Genome sequence of an industrial microorganism Streptomyces avermitilis: Deducing the ability of producing secondary metabolites
- S. Ōmura, H. Ikeda, M. Hattori
- Biology, EngineeringProceedings of the National Academy of Sciences…
- 25 September 2001
Streptomyces avermitilis is a soil bacterium that carries out not only a complex morphological differentiation but also the production of secondary metabolites, one of which, avermectin, is…
A small-molecule inhibitor of the bacterial type III secretion system protects against in vivo infection with Citrobacter rodentium
- Kyota Kimura, M. Iwatsuki, A. Abe
- BiologyJournal of antibiotics (Tokyo. )
- 1 February 2011
In vivo infection study using mice clearly indicated that the administration of aurodox allowed the mice to survive a lethal dose of Citrobactor rodentium, a model bacterium for human pathogens such as EPEC, and directly demonstrated for the first time that this putative T3SS inhibitor can be applied as a novel class of anti-infective agents.
Longispora albida gen. nov., sp. nov., a novel genus of the family Micromonosporaceae.
- A. Matsumoto, Yōko Takahashi, M. Shinose, A. Seino, Y. Iwai, S. Ōmura
- BiologyInternational Journal of Systematic and…
- 1 September 2003
A novel actinomycete strain was isolated from a soil sample collected in Japan by using gellan gum as a solidifying agent and it is proposed that this strain should be classified in a novel genus and species, Longispora albida gen. nov.
Actinophytocola oryzae gen. nov., sp. nov., isolated from the roots of Thai glutinous rice plants, a new member of the family Pseudonocardiaceae.
- Chantra Indananda, A. Matsumoto, Y. Inahashi, Yōko Takahashi, Kannika Duangmal, A. Thamchaipenet
- BiologyInternational Journal of Systematic and…
- 1 May 2010
It is proposed that strain GMKU 367(T) represents a novel species in a new genus in the family Pseudonocardiaceae, with the name Actinophytocola oryzae gen. nov., sp.Novel endophytic actinomycete isolated from roots of Thai glutinous rice plants.
In vitro and in vivo antimalarial activities of a non-glycosidic 18-membered macrolide antibiotic, borrelidin, against drug-resistant strains of Plasmodia.
- K. Otoguro, H. Ui, S. Ōmura
- Biology, MedicineJournal of antibiotics (Tokyo. )
- 25 August 2003
The antimalarial profile of borrelidin is reported here, a known nonglycosidic 18-membered macrolide antibiotic with a cyclopentanecarboxylic acid side chain, in comparison with those of clinically used antimalaria drugs.
Lariatins, Novel Anti-mycobacterial Peptides with a Lasso Structure, Produced by Rhodococcus jostii K01-B0171
- M. Iwatsuki, R. Uchida, S. Ōmura
- Biology, ChemistryJournal of antibiotics (Tokyo. )
- 1 June 2007
Two anti-mycobacterial peptides with a lasso structure, named lariatins A and B, were separated by HP-20 and ODS column chromatographies and purified by HPLC from the culture broth of Rhodococcus…
Borrelidin, a potent antimalarial: stage-specific inhibition profile of synchronized cultures of Plasmodium falciparum
- A. Ishiyama, M. Iwatsuki, K. Otoguro
- MedicineJournal of antibiotics (Tokyo. )
- 25 May 2011
Borrelidin, a potent antimalarial: stage-specific inhibition profile of synchronized cultures of Plasmodium falciparum
Patulibacter minatonensis gen. nov., sp. nov., a novel actinobacterium isolated using an agar medium supplemented with superoxide dismutase, and proposal of Patulibacteraceae fam. nov.
- Yōko Takahashi, A. Matsumoto, Kurimi Morisaki, S. Ōmura
- BiologyInternational Journal of Systematic and…
- 1 February 2006
On the basis of phenotypic and genotypic characteristics, it is proposed that strain KV-614T represents a new genus and a novel species, Patulibacter minatonensis gen. nov, in the class Actinobacteria.
Ilumatobacter fluminis gen. nov., sp. nov., a novel actinobacterium isolated from the sediment of an estuary.
- A. Matsumoto, Hiroki Kasai, Y. Matsuo, S. Ōmura, Y. Shizuri, Yōko Takahashi
- BiologyJournal of General and Applied Microbiology
- 1 June 2009
Bacterial strain YM22-133T was isolated from the sediment of an estuary and grew in media with an artificial seawater base and can be classified as a novel genus and species, Ilumatobacter fluminis gen. nov.
Isolation of new actinomycete strains for the screening of new bioactive compounds.
- Yōko Takahashi, S. Ōmura
- Biology, EngineeringJournal of General and Applied Microbiology
- 1 June 2003
9 novel bioactive compounds from actinomycete strains isolated under unusual conditions are discovered, and two new genera, five new species and one new subspecies are proposed.
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