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Evaluating bistability of Bax activation switch.

• Tingzhe Sun, Xuzhu Lin, Yinna Wei, Yichen Xu, Pingping Shen
• FEBS letters
• 2010

Mitochondrial apoptotic pathway is precisely controlled by BCL-2 family. Complex interactions of BCL-2 family proteins constitute a bistable switch of which detailed experimental and theoretical… (More)

Cell-death-mode switch from necrosis to apoptosis in hydrogen peroxide treated macrophages

• Xuzhu Lin, Tingzhe Sun, Meihong Cai, Pingping Shen
• Science China Life Sciences
• 2010

Cell death is typically defined either as apoptosis or necrosis. Because the consequences of apoptosis and necrosis are quite different for an entire organism, the investigation of the… (More)

Redox imbalance provokes deactivation of macrophages in sepsis.

• Ting C. Chen, Xuzhu Lin, Jiafa Xu, Renxiang Tan, Jianguo Ji, Pingping Shen
• Proteomics. Clinical applications
• 2009

Sepsis accounts for the majority of deaths in critically ill patients. Symptoms of septic disease are often associated with monocyte/macrophage desensitization. In the current study, impaired… (More)

Uncarboxylated Osteocalcin Enhances Glucose Uptake Ex Vivo in Insulin-Stimulated Mouse Oxidative But Not Glycolytic Muscle

• Xuzhu Lin, Lewan Parker, +5 authors Itamar Levinger
• Calcified Tissue International
• 2018

Uncarboxylated osteocalcin (ucOC) stimulates muscle glucose uptake in mice EDL and soleus muscles. However, whether ucOC also exerts a similar effect in insulin-stimulated muscles in a muscle… (More)

Hindlimb Immobilization, But Not Castration, Induces Reduction of Undercarboxylated Osteocalcin Associated With Muscle Atrophy in Rats.

• Xuzhu Lin, Erik D Hanson, Andrew C Betik, Tara C. Brennan-Speranza, Alan Hayes, Itamar Levinger
• Journal of bone and mineral research : the…
• 2016

Undercarboxylated osteocalcin (ucOC) has been implicated in skeletal muscle insulin sensitivity and function. However, whether muscle mass and strength loss in atrophic conditions is related to a… (More)

Recombinant Uncarboxylated Osteocalcin Per Se Enhances Mouse Skeletal Muscle Glucose Uptake in both Extensor Digitorum Longus and Soleus Muscles

• Xuzhu Lin, Lewan Parker, +5 authors Itamar Levinger
• Front. Endocrinol.
• 2017

Emerging evidence suggests that undercarboxylated osteocalcin (ucOC) improves muscle glucose uptake in rodents. However, whether ucOC can directly increase glucose uptake in both glycolytic and… (More)

Oxidative stress in malignant melanoma enhances tumor necrosis factor-α secretion of tumor-associated macrophages that promote cancer cell invasion.

• Xuzhu Lin, Wei Zheng, +6 authors Pingping Shen
• Antioxidants & redox signaling
• 2013

AIMS Malignant melanoma is well known for abundant reactive oxygen species (ROS) that exist in the primary tumor environment. Within this microenvironment, tumor-associated macrophages (TAMs) play… (More)

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