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Ataxia telangiectasia (A-T) is a multisystemic disease caused by mutations in the ATM (A-T mutated) gene. It strikes before 5 years of age and leads to dysfunctions in many tissues, including the CNS, where it leads to neurodegeneration, primarily in cerebellum. Alzheimer's disease (AD), by contrast, is a largely sporadic neurodegenerative disorder that(More)
PURPOSE This study is to examine how viewing a Japanese garden affects Japanese patients with dementia. BACKGROUND In a previous study, authors explored the effect on individuals with Alzheimer's disease of viewing an indoor Japanese garden at a nursing home in the United States and reported that viewing the garden significantly reduced the heart rate,(More)
which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed. Alerts: Sign up at eneuro.org/alerts to receive customized email alerts when the fully formatted version of this article is published. Neurons in vulnerable regions of the Alzheimer's disease brain display reduced ATM signaling(More)
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