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PURPOSE Investigating the discriminative brain map for patients with attention-deficit/hyperactivity disorder (ADHD) based on feature selection and classifier; and identifying patients with ADHD based on the discriminative model. MATERIALS AND METHODS A dataset of resting state fMRI contains 23 patients with ADHD and 23 healthy subjects were analyzed.(More)
Granger causality model (GCM) derived from multivariate vector autoregressive models of data has been employed to identify effective connectivity in the human brain with functional magnetic resonance imaging (fMRI) and to reveal complex temporal and spatial dynamics underlying a variety of cognitive processes. In the most recent fMRI effective connectivity(More)
Previous studies had reported that volume differences of gray matter (GM) in subcortical regions of the human brain were mainly caused by gender. Meanwhile, other studies had found that the distribution of GM in the human brain varied based on individual brain sizes. Main effects of volume differences of GM in subcortical regions remain unclear. Therefore,(More)
Signal variation in diffusion-weighted images (DWIs) is influenced both by thermal noise and by spatially and temporally varying artifacts, such as rigid-body motion and cardiac pulsation. Motion artifacts are particularly prevalent when scanning difficult patient populations, such as human infants. Although some motion during data acquisition can be(More)
Intrinsic connectivity networks (ICNs) are composed of spatial components and time courses. The spatial components of ICNs were discovered with moderate-to-high reliability. So far as we know, few studies focused on the reliability of the temporal patterns for ICNs based their individual time courses. The goals of this study were twofold: to investigate the(More)
PURPOSE Investigating the altered temporal features within and between intrinsic connectivity networks (ICNs) for boys with attention-deficit/hyperactivity disorder (ADHD); and analyzing the relationships between altered temporal features within ICNs and behavior scores. MATERIALS AND METHODS A cohort of boys with combined type of ADHD and a cohort of(More)
The brain active patterns were organized differently under resting states of eyes open (EO) and eyes closed (EC). The altered voxel-wise and regional-wise resting state active patterns under EO/EC were found by static analysis. More importantly, dynamical spontaneous functional connectivity has been observed in the resting brain. To the best of our(More)
OBJECTIVE To investigate the functional connectivity (FC) impairments within anterior and posterior default mode networks (aDMN and pDMN) for cirrhosis with minimal hepatic encephalopathy (MHE), and to analyze relationship between DMNs alterations with neurocognitive impairments. METHODS From March 2009 to December 2011, a total of 43 cirrhotic patients(More)