Xueyuan Chen

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Human serum albumin (HSA), a naturally abundant protein in blood plasma and tissue fluids, has an extraordinary ligand-binding capacity and is advocated as a drug carrier to facilitate drug delivery. To render it tumor targeting specificity, we generated a recombinant HSA fused with the amino-terminal fragment (ATF) of urokinase, allowing the fusion protein(More)
When retinoic acid-inducible gene 1 protein (RIG-I)-like receptors sense viral dsRNA in the cytosol, RIG-I and melanoma differentiation-associated gene 5 (MDA5) are recruited to the mitochondria to interact with mitochondrial antiviral signaling protein (MAVS) and initiate antiviral immune responses. In this study, we demonstrate that the biotin-containing(More)
Higher order multiphoton-pumped polarized lasers have fundamental technological importance. Although they can be used to in vivo imaging, their application has yet to be realized. Here we show the first polarized three-photon-pumped (3PP) microcavity laser in a single host-guest composite metal-organic framework (MOF) crystal, via a controllable in situ(More)
Ultrasensitive and accurate detection of tumor markers is of vital importance for the screening or diagnosis of cancers at their early stages and for monitoring cancer relapse after surgical resection. Inorganic lanthanide (Ln3+) nanoparticles (NPs), owing to their superior physicochemical characteristics, are regarded as a new generation of luminescent(More)
In article 1600197, Xueyuan Chen and co-workers report a novel luminescent bioassay technique, namely, dissolution-enhanced luminescence bioassay based on inorganic lanthanide nanoprobes, for ultrasensitive in-vitro detection of tumor markers in human sera or saliva, such as carcinoembryonic antigen, prostate specific antigen and alpha-fetoprotein, with(More)
Photodynamic therapy (PDT) is a promising therapeutic modality which uses a photosensitizer to capture visible light resulting in phototoxicity in the irradiated region. PDT has been used in a number of pathological indications, including tumor. A key desirable feature of the photosensitizer is the high phototoxicity on tumor cells but not on normal cells.(More)
With rapid development of computer science, the means of the agricultural park planning are renewed continuously. Based on the long-term practice in the agricultural park planning, we put forward innovatively the integrated information processing technology in three dimensions in the paper, that is, information, time and spatial dimensions, On the basis of(More)
Copyright 2007, Baldassare Di Bartolo and Ottavio Forte, shared with individual authors. This edition is intended for dissemination through electronic media and may be reproduced for scientific purposes. The entire book or an individual chapter may be printed-as long as the author's name(s) and relevant publication information remains attached and the(More)
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