Xuexu Chen

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 Nature has engineered a universe of redox proteins to efficiently control the oxidation and reduction of substrates and to convert redox energy into a delocalized transmembrane proton gradient power source. Some rapid physiologically relevant electron transfers are rate limited by electron tunneling. Distance appears to be the principle means naturally(More)
In this work we developed a novel label-free fluorescence sensing approach for the detection of nicotinamide adenine dinucleotide (NAD(+)) based on a dumbbell-like DNA probe designed for both ligation reaction and digestion reaction with low background noise. SYBR Green I (SG I), a double-helix dye, was chosen as the readout fluorescence signal. In the(More)
By coupling thin-film microextraction (TFME) with surface-enhanced Raman scattering (SERS), a facile method was developed for the determination of sulfur dioxide (SO2), the most effective food additive in winemaking technology. The TFME substrate was made by free settling of sea urchin-like ZnO nanomaterials on a glass sheet. The headspace sampling (HS)(More)
A novel label-free turn-on fluorescence biosensor for the determination of streptavidin (SA) was proposed. Using terminal protection of small molecule-linked DNA chimeras, which can protect DNA from degradation by various exonucleases when the small molecule moieties are bound to their protein target, we designed a loop probe, where the 3'-end was modified(More)
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