Xuewei Yang

Learn More
Metastasis is responsible for the rapid recurrence and poor survival of malignancies. Epithelial-mesenchymal transition (EMT) has a critical role in metastasis. Increasing evidence indicates that EMT can be regulated by microRNAs (miRNAs). The aim of this study was to investigate the role of miR-26b in modulating epithelial-mesenchymal transition (EMT) in(More)
BACKGROUND Our previous studies showed that glioma-associated oncogene (Gli)2 plays an important role in the proliferation and apoptosis resistance of hepatocellular carcinoma (HCC) cells. The aim of this study was to explore the clinical significance of Gli2 expression in HCC. METHODS Expression of Gli2 protein was detected in samples from 68 paired HCC(More)
JEL classification: G22 G33 MSC: 91B30 60J75 60H10 Keywords: Risk model Barrier strategy Lévy process Two-sided jump Time of ruin Deficit Expected discounted dividend Optimal dividend barrier Integro-differential operator Double exponential distribution Reflected jump-diffusions Laplace transform a b s t r a c t In this paper, we consider a general Lévy(More)
Hepatocellular carcinoma (HCC) is one of the common malignancies, which is highly metastatic and the third common cause of cancer deaths in the world. The invasion and metastasis of cancer cells is a multistep and complex process which is mainly initiated by extracellular matrix (ECM) degradation. Aberrant expression of microRNA has been investigated in HCC(More)
We have screened 11 isoquinoline derivatives and α-methylene-γ-butyrolactones using the 3-(4,5-dimethylthi-azol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) cytotoxicity assay in HeLa and HEK-293T cells. Compound 2 was identified as potential anticancer agent. To further improve its therapeutic potential, this agent was incorporated into transferrin(More)
The pre-mRNA splicing regulator serine-arginine protein kinase 1 (SRPK1) promotes cancer development and various pathophysiological processes. However, the clinical relevance of SRPK1 in hepatocellular carcinoma (HCC) is not clear. This study investigates the expression and prognostic value of SRPK1 in HCC. We found that SRPK1 expression was significantly(More)
6 We propose a new numerical scheme for a class of one-dimensional reflected stochastic differential equations (SDEs) by virtue of their explicit solutions, which enables us to carry out the simulation of this class of reflected SDEs by simulating some related SDEs without reflections. The new scheme yields the same order of convergence as the scheme for(More)
The improvement of lignin pyrolysis by biopretreatment of white-rot fungi was investigated in this study. Results showed that biopretreatment can decrease the final residue yields, increase the weight loss rates, and absorb less heat during the pyrolysis of lignin in the inert atmosphere. In addition, the activation energies of biopretreated lignin were(More)
A distributed map data parallel dissemination system, which can be used to distribute spatial map data to remote users through different networks, is presented. The paper first defines spatial map data, associated metadata and network resource nodes with graphic formalization definition. Then, the relations between map data and network resources are(More)