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Lysine-specific demethylase 5C promotes hepatocellular carcinoma cell invasion through inhibition BMP7 expression
BackgroundHepatocellular carcinoma (HCC) is the most common type of tumor and is associated with high morbidity and mortality rates. Patients with HCC routinely undergo surgery followed by adjuvantExpand
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HOXB9 promotes epithelial-to-mesenchymal transition via transforming growth factor-β1 pathway in hepatocellular carcinoma cells
The function of the epithelial-to-mesenchymal transition (EMT) during hepatocellular carcinoma (HCC) progression is well established. However, the regulatory mechanisms modulating this phenomenonExpand
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Hyperfibrinogenemia predicts poor prognosis in patients with advanced biliary tract cancer
  • H. Li, Tong Zhao, +5 authors R. Wang
  • Medicine
  • Tumor Biology
  • 1 March 2016
Hyperfibrinogenemia reportedly predicts poor prognosis in several cancers but has not been reviewed for biliary tract cancer (BTC). The aim of the present study was to evaluate associations betweenExpand
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Homeobox B9 is overexpressed in hepatocellular carcinomas and promotes tumor cell proliferation both in vitro and in vivo.
HomeoboxB9 (HOXB9), a nontransforming transcription factor that is overexpressed in multiple tumor types, alters tumor cell fate and promotes tumor progression. However, the role of HOXB9 inExpand
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Trametes robiniophila may induce apoptosis and inhibit MMPs expression in the human gastric carcinoma cell line MKN-45.
Gastric carcinoma (GC) is one of the most common malignant tumors and is mainly treated by invasive surgeries. The present study aimed to investigate the treatment potential of Trametes robiniophilaExpand
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Real‐world data of lapatinib and treatment after lapatinib in patients with previously treated HER2‐positive metastatic breast cancer: A multicenter, retrospective study
Lapatinib is widely used in the later lines treatment of HER2 positive metastatic breast cancer (MBC). EGF104900 study suggested that among patients who experienced progression on priorExpand
Abstract 21: Mutation profiling of patients with multiple primary cancers reveals some common genomic alterations in signaling pathways
Multiple primary cancers in a single individual are rare and usually challenging for effective treatments. Identification common cancer gene driver mutations and targets for patients with multipleExpand
Establishment of the cultured model of microencapsulated human gastric carcinoma cells SGC-7901
Objective To establish the cultured model of microencapsulated human gastric carcinoma (HGC) cell line SGC-7901.Methods The SGC-7901 cells were cultured and encapsulated in APA microcapsules usingExpand
Abstract 2288: Cell-surface vimentin as a novel biomarker for detecting circulating tumor cells from advanced gastric cancer patients
Background: Aberrant activation of epithelial-mesenchymal transition (EMT) is closely associated with gastric cancer (GC) progression and metastasis. However, biomarkers specifically capturingExpand
The prognostic role of a combined fibrinogen and inflammation- based index in patients with metastatic breast cancer
Department of Oncology, Affiliated Zhongshan Hospital of Dalian University, Dalian, China; The Key Laboratory of Biomarker High Throughput Screening and Target Translation of Breast andExpand