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With the development of parallel computing, distributed computing, grid computing, a new computing model appeared. The concept of computing comes from grid, public computing and SaaS. It is a new method that shares basic framework. The basic principles of cloud computing is to make the computing be assigned in a great number of distributed computers, rather(More)
It is a great idea to make many normal computers together to get a super computer, and this computer can do a lot of things. This is the concept of cloud computing. Cloud computing is an emerging model of business computing. And it is becoming a development trend. This article compares cloud computing and grid computing. Internet has connected all the(More)
To date there are few compounds known to pharmacologically discriminate between alpha1 and alpha3 subunit-containing glycine receptors (GlyRs). The present study stemmed from an observation that the glycinergic agonists, taurine and beta-alanine, act with much lower agonist efficacy at alpha3 GlyRs than at alpha1 GlyRs. We sought to understand the(More)
The dihydropyridines (DHPs), nifedipine and nicardipine, modulate native glycine receptors (GlyRs) at micromolar concentrations. Nicardipine has a biphasic potentiating and inhibitory effect, whereas nifedipine causes inhibition only. The present study sought to investigate (1) the molecular mechanism by which these compounds inhibit recombinant GlyRs, and(More)
As a kind of emerging business computational model, Cloud Computing distribute computation task on the resource pool which consists of massive computers, accordingly ,the application systems can gain the computation strength, the storage space and software service according to its demand. Cloud computing can be viewed from two different aspects. One is(More)
beta-Carbolines are potent modulators of GABA type A receptors and they have recently been shown to inhibit glycine receptors in a subunit-specific manner. The present study screened four structurally similar beta-carbolines, 1,2,3,4-tetrahydronorharmane, norharmane, harmane and 6-methoxyharmalan, at recombinantly expressed alpha1, alpha1beta, alpha2 and(More)
Feature selection and weighting is one of the key problem in text categorization. The chief obstacles to feature selection are noise and sparseness. This paper presents an approach of Chinese text feature selection and weighting based on semantic statistics. First, we use synonymous concepts to extract feature values in text based on Thesaurus which names(More)
In Security-as-a-service model the focus is on security provided as cloud services; i. e. security delivered through the cloud instead of on-premise security solutions. The security-as-a-service model can also enhance functionality of existing on-premise implementations by working as a hybrid solution. The paper provides the comprehensive analysis of(More)
Bilobalide, a major bioactive component of Ginkgo biloba herbal extracts, exhibits neuroprotective and anti-ischaemic activity. However, its therapeutic potential is limited because of its instability. Attempts to synthesise a more stable analogue culminated in the development of NV-31. This compound recapitulates some aspects of bilobalide pharmacology.(More)