Xue-song Tian

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It is recognized in recent years that activation of delta-opioid receptor (DOR) elicits neuroprotection against hypoxia and ischemia. However, the underlying mechanisms are not well understood yet. Mitochondrial dysfunction plays a key role in hypoxic neuronal injury, but the effect of DOR activation on neurons with a mitochondrial respiratory chain(More)
This work was performed to determine the role of delta-opioid receptor (DOR) in protection against acute ischemia/reperfusion injury. Transient (1 h) focal cerebral ischemia was induced by middle cerebral artery occlusion (MCAO). DOR agonist TAN-67 (30 nmol, 60 nmol, 200 nmol), DOR antagonist naltrindole (20 nmol, 50 nmol, 100 nmol) or artificial cerebral(More)
The effect of substance P (SP) on the activities of oviductal isthmic smooth muscle in rabbits was studied. Rabbits were divided into estrous, diestrous and ovariectomized groups. The results were as follows: (1) SP suppressed the activity of the oviductal isthmic smooth muscle in diestrous rabbit (P less than 0.05). (2) SP did not suppress the activities(More)
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