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Oxidative injury has been implicated in the etiology of Parkinson's disease (PD). Gypenosides (GPs), the saponins extract derived from the Gynostemma pentaphyllum, has various bioactivities. In this study, GPs was investigated for its neuroprotective effects on the 1-methyl-4-phenylpyridinium ion (MPP(+))-induced oxidative injury of dopaminergic neurons in(More)
In present study, in vivo electrophysiological techniques were applied to examine the effects of anterior cingulate cortex (ACC) activation on mechanical and electrical stimuli-evoked responses in rat spinal cord wide-dynamic-range (WDR) neurons. We found that bilateral ACC electrical stimulation (100Hz, 20V, 20s) had different effects on neuronal responses(More)
Bacillus megaterium is a soil-inhabiting Gram-positive bacterium that is routinely used in industrial applications for recombinant protein production and bioremediation. Studies involving Bacillus megaterium isolated from waterfowl are scarce. Here, we report a 6.26-Mbp draft genome sequence of Bacillus megaterium BHG1.1, which was isolated from feces of a(More)
BACKGROUND Opiate addiction remains intractable in a large percentage of patients, and relapse is the biggest hurdle to recovery because of psychological dependence. Multiple studies identify a central role of the nucleus accumbens (NAc) in addiction; several studies note decreased addictive behavior after interventions in this area. METHODS Based on(More)
Yan-Dan Ren1,*, Zhen-Shi Ye1,*, Liu-Zhu Yang1,*, Li-Xin Jin1, Wen-Jun Wei1, Yong-Yue Deng2, Xiao-Xiao Chen2, Chuan-Xing Xiao1, Xiao-Fang Yu3, Hong-Zhi Xu1, Li-Zhu Xu1, Yun-Na Tang1, Fei Zhou1, Xue-Lian Wang2, Mei-Ya Chen1, Li-Gang Chen1, Mei-Zhu Hong4, Jian-Lin Ren1, Jin-Shui Pan1 1Zhongshan Hospital Department of Gastroenterology, Xiamen University,(More)
Oscillation activities are the feature of neural network and correlated to different physiological states. The theta (θ) oscillation (2–7 Hz) has been reported in the basal ganglia, and the intrinsic resonance properties of individual neurons have provided a basis for this network oscillation. The basal ganglia neurons receive comprehensive modulation(More)
BACKGROUND Medullary thyroid carcinoma (MTC) is a rare malignant tumour and usually difficult to diagnose with ultrasound. The aim of the study is to summarize the sonographic features of MTC and evaluate their diagnostic values. METHODS We analyzed the sonographic features of 35 MTCs and 50 benign nodules with respect to nodular size, echogenecity,(More)
Nigrostriatal neurons expressing RET protein, a receptor protein tyrosine kinase of glial cell line-derived neurotrophic factor (GDNF) were investigated in rats using retrograde neural tracing with horseradish peroxidase (HRP) combined with immunohistochemistry. HR/RET double-labeled neurons were abundantly distributed in the substantia nigra pars compacta(More)
We studied the effect of stereotactic surgery in cases of alcohol dependence. Twelve patients with a psychological dependence on alcohol (treated systematically with medication for detoxification 3-8 times in various rehabilitation centers before, but had relapsed within 2 weeks after withdrawal) were treated by ablating the nucleus accumbens (NA(C))(More)
A retrospective study was performed on case reports of Pneumocystis pneumonia (PCP) from 1959 to 2009 in mainland China. The epidemiological characteristics of PCP over half a century were investigated over two time spans. The first was from 1959, when the first incidence of PCP was reported, to 1984, before the emergence of AIDS in mainland China. The(More)