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Nasopharyngeal carcinoma (NPC) is an Epstein-Barr virus (EBV) associated malignancy with high prevalence in Southern Chinese. In order to assess whether defects of EBV-specific immunity may contribute to the tumor, the phenotype and function of circulating T-cells and tumor infiltrating lymphocytes (TILs) were investigated in untreated NPC patients.(More)
AIM To explore the correlation between and nasopharyngeal carcinoma the polymorphism of HLA-A, B and DRB1 alleles in the south of China. METHODS The genotypes of HLA-A, B and DRB1 alleles in 35 patients with NPC and 60 healthy controls were determined by PCR-sequence-specific primer (PCR-SSP). RESULTS The frequency of HLA-A * 02, HLA-B * 58 and HLA-DRB1(More)
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