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Current clinical therapies for critical-sized bone defects (CSBDs) remain far from ideal. Previous studies have demonstrated that engineering bone tissue using mesenchymal stem cells (MSCs) is feasible. However, this approach is not effective for CSBDs due to inadequate vascularization. In our previous study, we have developed an injectable and porous nano(More)
Endostar, approved for the treatment of non-small-cell lung cancer by the State Food and Drug Administration in China, is a derivative of human endostatin that is modified with an additional metal-chelating sequence (MGGSHHHHH) at the N-terminus. This modification contributes to an additional zinc-binding site in the endostatin sequence. In the present(More)
Primary cilia are microtubule-based organelles that project from the cell surface to enable transduction of various developmental signaling pathways. The process of intraflagellar transport (IFT) is crucial for the building and maintenance of primary cilia. Ciliary dysfunction has been found in a range of disorders called ciliopathies, some of which display(More)
Heat shock transcription factors (Hsfs) are the terminal components of the signal transduction chain mediating the activation of genes responsive to both heat stress and a large number of chemical stressors. This paper aims to clone Hsf from lily and characterize its function by analyses of mRNA expression, transactivation activity and thermotolerance of(More)
Most of the existing traffic sign recognition (TSR) systems make use of the inner region of the signs or the local features such as Haar, histograms of oriented gradients (HOG), and scale-invariant feature transform for recognition, whereas these features are still limited to deal with the rotation, illumination, and scale variations situations. A good(More)
Lipopolysaccharide (LPS), one of the most prominent pathogen-associated molecular patterns (PAMPs), activates macrophages, causing release of toxic cytokines (i.e. tumor necrosis factor (TNF)-α) that may provoke inflammation and endotoxin shock. Here, we tested the potential role of trametinib, a novel and highly potent MAPK/ERK kinase (MEK) inhibitor,(More)
Virus-induced gene silencing (VIGS) system could be performed successfully in Gladiolus hybridus with vacuum infiltration of cormels and young plants. Functional analysis of genes in gladiolus has previously been impractical due to the lack of an efficient stable genetic transformation method. However, virus-induced gene silencing (VIGS) is effective in(More)
Diseases control is always an issue in cotton production, the timely detection and effective control of diseases depend on, in most cases, an effective diagnosis system. Based on the distribution of cotton diseases in the main yielding areas of China in recent years, the main species and characters of cotton diseases were listed classified in the study and(More)
The face is a complex multidimensional visual model and developing a computational model for face recognition is difficult. In this paper, we present a method for face recognition based on parallel neural networks. Neural networks (NNs) have been widely used in various fields. However, the computing efficiency decreases rapidly if the scale of the NN(More)