Xue Qi Zhao

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Although the mechanism underlying C-type natriuretic peptide (CNP) beneficial effects is not entirely understood, modulating the expression of matrix metalloproteinases (MMPs)/tissue inhibitors of metalloproteinases (TIMPs) may play an important role. The study presented herein was designed as a first demonstration of the regulative effects of CNP on(More)
Enterovirus 71 (EV71), as a member of the Picornaviridae family, is characterized by a single positive-strand genomic RNA known to cause hand, foot, and mouth disease (HFMD) in children. Since the first identification of EV71 infection in California in 1969, periodic epidemics have broken out worldwide [1]. In China, the first EV71 strain was isolated in(More)
INTRODUCTION C-type natriuretic peptide (CNP) selectively binds to the guanylyl cyclase coupled natriuretic peptide receptor (NPR)-B and exerts more potent antihypertrophic and antifibrotic properties. Elimination of CNP occurs mainly by neutral endopeptidase (NEP) and NPR-C. METHODS We established a rat model of unilateral ureteral obstruction (UUO) to(More)
OBJECTIVE AND METHODS This study established a simple stereological method to obtain quantitative information about two- or three-dimensional structures based on observations from kidney sections in the unilateral ureteral obstruction(UUO) model. RESULTS Tubulointerstitial area(TA) and TA/the area of a rectangular field(RA) were raised gradually, but(More)
This paper is to investigate the apoptosis effect of ovarian cancer SKOV3 cells induced by nanosecond plused electric fileds (nsPEFs) and to study its influence on Fas-mediated apoptosis. SKOV3 cell were exposed to the 45kV/cm of field intensity, 30 pulses, and 50ns, 100ns, and 200ns of pulse width, respectively. Flow cytometry were used to assay apoptosis.(More)
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