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Innate immunity provides the first line of host defense against invading microbial pathogens. This defense involves retinoic acid-inducible gene-I-like receptors that detect viral RNA and activate the mitochondrial antiviral-signaling (MAVS) protein, an adaptor protein, leading to activation of the innate antiviral immune response. The mechanisms by which(More)
The ribonucleoprotein (RNP) of the influenza A virus is responsible for the transcription and replication of viral RNA in the nucleus. These processes require interplay between host factors and RNP components. Here, we report that the Fragile X mental retardation protein (FMRP) targets influenza virus RNA synthesis machinery and facilitates virus(More)
There are a lot of factors that affect the cost of logistics services .And when we try to give a specific price for customers, we should take into account for various factors to make our service and our price have a best match. It can reflect the tailored of logistics services. In this paper we take the warehousing & distribution enterprise as an example,(More)
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Tripartite motif-containing 14 (TRIM14) is a mitochondrial adaptor that facilitates innate immune signaling. Upon virus infection, the expression of TRIM14 is significantly induced, which stimulates the production of type-I IFNs and proinflammatory cytokines. As excessive immune responses lead to harmful consequences, TRIM14-mediated signaling needs to be(More)
Because the expense is quite high if we want to increase the radar intelligent BIT testability through hardware maintenance approaches. In this paper, for the first time we adopt the software engineering thinking-structural method to model radar intelligent BIT software. In the end, we present an intelligent BIT software modeling based on Multi-Agent. In(More)
OBJECTIVE To investigate whether pilose antler blood wine has the effects of estrogen-like activity and antioxidant in the ovariectomized (OVX) female rats. METHODS The rat model of oxidative stress was established by ovariectomy. The female rats were divided into 6 groups: normal control group, OVX group, base wine group, and 3 pilose antler blood wine(More)
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