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This review presents the latest developments in the field of carba-nucleosides (1994-1998). Special attention is paid to the synthesis of key precursors to those carba-nucleosides that possess significant biological activities or have novel structures.
The essential matter of urban traffic control is to timely evacuate the most potential congesting movement in an intersection. Distributed multi-agent system could efficiently disassemble the globe control of regional signal system into the local and single traffic controller with autonomously intelligent actions. The paper discusses a flexible structure… (More)
An improved route was developed for the preparation of the dinucleotide hybrid 5'-O-phosphoryl-2'-deoxycytidylyl-(3'--> 5')adenosine (pdCpA) 7. This simple and concise synthesis involves the successive coupling of 2-cyanoethyl N, N, N', N'-tetra- isopropylphosphorodiamidite with 4-N-benzoyl-5'-O-(4, 4'-dimethoxytrityl)-2'-deoxy-cytidine 1 and… (More)