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DNA methylation changes of whole blood cells in response to active smoking exposure in adults: a systematic review of DNA methylation studies
- Xu Gao, M. Jia, Y. Zhang, L. Breitling, H. Brenner
- Biology, Medicine
- Clinical Epigenetics
- 16 October 2015
Active smoking is a major preventable public health problem and an established critical factor for epigenetic modification. In this systematic review, we identified 17 studies addressing the… Expand
MicroRNA-26 governs profibrillatory inward-rectifier potassium current changes in atrial fibrillation.
- Xiaobin Luo, Zhenwei Pan, +20 authors S. Nattel
- Biology, Medicine
- The Journal of clinical investigation
- 1 May 2013
Atrial fibrillation (AF) is a highly prevalent arrhythmia with pronounced morbidity and mortality. Inward-rectifier K+ current (IK1) is believed to be an important regulator of reentrant-spiral… Expand
Behavioral adaptation of Pallas's squirrels to germination schedule and tannins in acorns
Using acorns from Castanea henryi (CH) and Quercus variabilis (QV) with contrasting germination schedule (related to food perishability) and tannin levels, we conducted field experiments in a… Expand
Long non-coding RNA metastasis associated in lung adenocarcinoma transcript 1 derived miniRNA as a novel plasma-based biomarker for diagnosing prostate cancer.
Examining plasma RNA is an emerging non-invasive diagnosis technique. However, whether tumour-derived long non-coding RNAs (lncRNAs) in plasma can be used as a novel approach to detect human prostate… Expand
Long noncoding RNAs: novel players in colorectal cancer.
Colorectal cancer (CRC) is the most common type of cancer in the world. Despite its commonness, the underlying mechanism of CRC is not completely understood. Long noncoding RNAs (lncRNAs) have… Expand
Frequency-dependent selection by tree squirrels: adaptive escape of nondormant white oaks
Frequency-dependent selection is theoretically predicted to have an important impact on predator--prey dynamics, but little is understood about this process in nature. We investigated oak--squirrel… Expand
Long noncoding RNA MALAT-1 is a new potential therapeutic target for castration resistant prostate cancer.
PURPOSE To understand the role of MALAT-1 in prostate cancer we evaluated its expression in prostate cancer tissues and cell lines. We also studied the therapeutic effects of MALAT-1 silencing on… Expand
The prostate cancer-up-regulated long noncoding RNA PlncRNA-1 modulates apoptosis and proliferation through reciprocal regulation of androgen receptor.
OBJECTIVE Emerging evidences implicate long noncoding RNAs (lncRNAs) are deregulated in cancer development. The purpose of the current study is to investigate the role of new lncRNA, named PlncRNA-1,… Expand
Occurrence, fate and ecotoxicological assessment of pharmaceutically active compounds in wastewater and sludge from wastewater treatment plants in Chongqing, the Three Gorges Reservoir Area.
- Q. Yan, Xu Gao, +5 authors J. Guo
- Chemistry, Medicine
- The Science of the total environment
- 1 February 2014
The occurrence, removal and ecotoxicological assessment of 21 pharmaceutically active compounds (PhACs) including antibiotics, analgesics, antiepileptics, antilipidemics and antihypersensitives, were… Expand
Prostate cancer in Asia: A collaborative report
The incidence of prostate cancer (PCa) within Asian population used to be much lower than in the Western population; however, in recent years the incidence and mortality rate of PCa in some Asian… Expand