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The CT uroscan consists of three to four time-spaced acquisitions of the same patient. After registration of these acquisitions, the data forms a volume in which each voxel contains a vector of elements corresponding to the information of the CT uroscan acquisitions. In this paper we will present a segmentation tool in order to differentiate the anatomical(More)
PURPOSE A good plan is crucial to the success of gamma knife treatment, which depends not only on parameters such as the number of shots, shot position, collimator sizes, and shot weight, but also on the number of blocked cobalt sources. However, during treatment, a plug is generally used to block those cobalt sources, so the beam cannot reach critical(More)
PURPOSE This article presents a new optimization method for stereotactic radiosurgery treatment planning for gamma unit treatment system. METHODS AND MATERIALS The gamma unit has been utilized in stereotactic radiosurgery for about 30 years, but the usual procedure for a physician-physicist team to design a treatment plan is a trial-and-error approach.(More)
The gamma unit is used to irradiate a target within the brain. During such a treatment many parameters, including the number of shots, the coordinates, the collimator size and the weight associated with each shot, affect the amount of dose delivered to the target volume and to the surrounding normal tissues. Hence it is not easy to determine an appropriate(More)
During a treatment using the Leksell gamma unit, the physician and physicist need to determine a treatment plan by changing the parameters such as collimator sizes, the position of isocenters and isocenters' weights. This is a complex problem because the set of parameters is large, especially when targets are geometrically close to a critical structure. For(More)
Previous studies that investigated the relationship between DM and survival in renal cell carcinoma (RCC) patients reported inconsistent findings. Hence, we conducted a meta-analysis to obtain a more precise evaluation of the prognostic significance of DM in RCC. A systematic review was conducted with PubMed, Embase, and Web of Science to identify relevant(More)
OBJECTIVES The von Hippel-Lindau (VHL) gene acts as a tumor suppressor in most clear cell renal cell carcinomas (ccRCCs). Tumor growth in ccRCCs relies on many factors that result from the loss of VHL. This study aims to identify new microRNAs with therapeutic potential for VHL-inactivated ccRCCs. MATERIALS AND METHODS We used 786O, A498 (VHL(More)
The modified discrete cosine transform (MDCT) and the inverse MDCT (IMDCT) are two of the most computationally intensive operations in layer III of MPEG audio coding standard. In this letter, we present a radix-3 algorithm for efficiently computing the MDCT and the corresponding IMDCT of a sequence with length N=2times3<sup>m</sup>. Comparison of the(More)