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OBJECTIVES The randomized, double-blinded, placebo-controlled study evaluated the administration of local infiltration of magnesium combined with ropivacaine to reduce pain scores after pediatric adenotonsillectomy. METHODS Sixty one subjects received 5ml solution contained 0.25% ropivacaine plus 5mg/kg magnesium sulphate (Group M+R), 5ml 0.25%(More)
BACKGROUND Magnesium can potentiate the antinociceptive effect of morphine. This prospective randomized double-blinded study was undertaken to establish the analgesic effect of adding magnesium to epidural morphine during cesarean section. METHODS Two hundred patients undergoing cesarean section under combined spinal-epidural anesthesia were recruited.(More)
AIM Polyps are a common cause of hematochezia in children, but the pathogenesis of polyps is unclear. The aim of this study was to investigate the relationship between Helicobacter pylori (HP) infection and colorectal polyps in children. METHODS Thirty-five patients who had undergone polypectomy after the detection of polyps served as the case group.(More)
Minocycline has been implicated in the treatment for multiple diseases in the nervous system for its neuroprotective properties. However, the mechanism by which minocycline benefits postoperative anesthesia-induced cognitive dysfunction is still unclear. In this study, we introduced minocycline to a rat model of anesthetic-induced learning and memory(More)
Security is an important issue in research and appliance of grid computing. Grid security model is composed of a series of mechanism and strategy to solve various practical security problems. This paper presents a grid security model based on virtual organization referring to GSI (a security component in Globus). The model consists of a logical model and a(More)
OBJECTIVE A meta-analysis was performed to explore the role of peri-operative bupivacaine infiltration in the relief of pain in adenotonsillectomy. METHODS Data from Medline, EMBase, Springer and the Cochrane Collaboration database were searched. Reference lists from identified publications were scanned. RevMan 5.0 software was used for statistical(More)
The present study was designed to determine the effects of chronic intermittent hypoxia (CIH) on pain sensitivity and the changes in the expression of delta-opioid receptor (DOR), mu-opioid receptor (MOR), and hypoxia-inducible factor (HIF)-1α and their relationship with pain sensitivity under hypoxia. CIH was employed to model the low oxygen condition in(More)
Current therapies for cancer-induced bone pain (CIBP) are still limited. Until recently, the molecular mechanisms underlying the spinal cell-mediated CIBP remain largely unknown. To better understand the role of spinal cells in CIBP, we investigated the role of spinal neuregulin1 (NRG1)‑ErbB2 signaling pathway in CIBP. In this study, a rat model of CIBP was(More)
Effective axon regeneration is achieved mainly by precise regulation of gene expression after peripheral nerve injury. MicroRNAs play an important role in controlling axon regeneration owe to its key epigenetic function in regulating gene expression. Here, we reveal that microRNA-9 (miR-9) may be a new suppressor of axon regeneration and FoxP1 is the(More)
Minocycline has been demonstrated to exert neuroprotective effects in various experimental models. In the present study, we investigated the mechanisms underlying the protective effects of minocycline on cell injury induced by the inhalation of the anesthetic, sevoflurane. In our in vivo experiments using rats, minocycline attenuated sevoflurane-induced(More)