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Delivery of chemo-sensitizing siRNAs to HER2+-breast cancer cells using RNA aptamers
Human epidermal growth factor receptor 2 (HER2) expression in breast cancer is associated with an aggressive phenotype and poor prognosis, making it an appealing therapeutic target. Trastuzumab, anExpand
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A new Lagerstätte from the Middle Ordovician St. Peter Formation in northeast Iowa, USA
A new fossil fauna has been discovered from a recently recognized shale unit within the middle Ordovician St. Peter Formation in northeast Iowa. It contains a variety of invertebrates andExpand
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CHANGES IN ANTIOXIDATIVE METABOLISM ACCOMPANYING PITTING DEVELOPMENT IN STORED BLUEBERRY FRUIT
Abstract Blueberries ( Vaccinium spp. ‘LanFeng’) are harvested and consumed at maturation and have a short storage life at room temperature. Changes in blueberry quality and physiological parametersExpand
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METTL3-mediated m6A modification is required for cerebellar development
N6-methyladenosine (m6A) RNA methylation is the most abundant modification on mRNAs and plays important roles in various biological processes. The formation of m6A is catalyzed by a methyltransferaseExpand
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Structural Insights into Substrate Selectivity, Catalytic Mechanism, and Redox Regulation of Rice Photosystem II Core Phosphatase.
Photosystem II (PSII) core phosphatase (PBCP) selectively dephosphorylates PSII core proteins including D1, D2, CP43, and PsbH. PBCP function is required for efficient degradation of the D1 proteinExpand
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Structural Insights into Substrate Selectivity, Catalytic Mechanism, and Redox Regulation of Rice Photosystem II Core Phosphatase
Photosystem II (PSII) core phosphatase (PBCP) selectively dephosphorylates PSII core proteins including D1, D2, CP43, and PsbH. PBCP function is required for efficient degradation of the D1 proteinExpand
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Imidazole Compounds for Protecting Choroidal Endothelial Cells from Complement Injury
Age-related macular degeneration (AMD) is a common, blinding disease associated with increased complement system activity. Eyes with AMD show elevated accumulation of the membrane attack complexExpand
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Studies on the Mechanism of Increasing Yield and Income of the Intercropping System with Maize and Soybean in Upland of Red Soil
This article analyzes the effect of increasing yield and income of the intercropping system with maize and soybean in upland of red soil ,and explains the influence of intercropping on plant growthExpand
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Molecular and functional diversity of organelle RNA editing mediated by RNA recognition motif-containing protein ORRM4 in tomato.
Plant organellar RNA editing is a distinct type of post-transcriptional RNA modification that is critical for plant development. We showed previously that the RNA editing factor SlORRM4 is requiredExpand
Solutions and dispersions of solid state drugs poorly soluble in water.
The invention describes a composition useful as a pharmaceutical excipient, the production process thereof and pharmaceutical compositions thus produced. In particular, the invention is applied toExpand