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Structure and function of a potent lipopolysaccharide-binding antimicrobial and anti-inflammatory peptide.
Antimicrobial peptides (AMPs) play pivotal roles in the innate defense of vertebrates. A novel AMP (cathelicidin-PY) has been identified from the skin secretions of the frog Paa yunnanensis .… Expand
A Designed Tryptophan- and Lysine/Arginine-Rich Antimicrobial Peptide with Therapeutic Potential for Clinical Antibiotic-Resistant Candida albicans Vaginitis.
- Lin Jin, Xuewei Bai, +8 authors Qiumin Lu
- Medicine, Chemistry
- Journal of medicinal chemistry
- 29 February 2016
New therapeutic agents for Candida albicans vaginitis are urgently awaiting to be developed because of the increasing antibiotic resistance of C. albicans. Antimicrobial peptides (AMPs) are one of… Expand
Isolation, characterization and molecular cloning of new antimicrobial peptides belonging to the brevinin-1 and temporin families from the skin of Hylarana latouchii (Anura: Ranidae).
Around 40 species of Hylarana amphibians are distributed in tropical and subtropical Asia, and Chinese broad-folded frog, Hylarana latouchii (Boulenger, 1899) is one of them. In this study, six… Expand
An immunoregulatory peptide from salivary glands of the horsefly, Hybomitra atriperoides.
- Xiuwen Yan, H. Feng, Haining Yu, Xiaolong Yang, J. Liu, R. Lai
- Medicine, Biology
- Developmental and comparative immunology
Horseflies are economically important blood-feeding arthropods and also a nuisance for humans, and vectors for filariasis. They rely heavily on the pharmacological propriety of their saliva to get… Expand
Bi-functional peptides with both trypsin-inhibitory and antimicrobial activities are frequent defensive molecules in Ranidae amphibian skins
Amphibian skins act as the first line against noxious aggression by microorganisms, parasites, and predators. Anti-microorganism activity is an important task of amphibian skins. A large amount of… Expand
An Immunosuppressant Peptide from the Hard Tick Amblyomma variegatum
Ixodid ticks are well known for spreading transmitted tick-borne pathogens while being attached to their hosts for almost 1–2 weeks to obtain blood meals. Thus, they must secrete many… Expand
A novel cysteine-rich antimicrobial peptide from the mucus of the snail of Achatina fulica
Antimicrobial peptides (AMPs) are important components of the innate immunity. Many antimicrobial peptides have been found from marine mollusks. Little information about AMPs of mollusks living on… Expand
A novel defensin-like antimicrobial peptide from the skin secretions of the tree frog, Theloderma kwangsiensis.
Defensins are one of the major families of antimicrobial peptides (AMPs), and have been reported from prokaryotic to eukaryotic kingdoms. But defensins are seldom found in amphibian which is a major… Expand
The cathelicidin-like peptide derived from panda genome is a potential antimicrobial peptide.
A novel cathelicidin-like antimicrobial peptide was identified by mining genome of panda. This peptide (cathelicidin-AM) was synthesized. It showed potential antimicrobial activities against wide… Expand
Identification of a putative flavin adenine dinucleotide-binding monooxygenase as a regulator for Myxococcus xanthus development.
- Shanshan Cao, Miaomiao Wu, Shihui Xu, Xiuwen Yan, X. Mao
- Medicine, Biology
- Journal of bacteriology
- 1 April 2015
UNLABELLED Gene clusters coding for the chaperone/usher (CU) pathway are widely distributed in many important environmental and pathogenic microbes; however, information about the regulatory… Expand