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Liquorice, a unique "guide drug" of traditional Chinese medicine: a review of its role in drug interactions.
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Absorption and Disposition of Ginsenosides after Oral Administration of Panax notoginseng Extract to Rats
TLDR
Rat exposure to ginsenosides Ra3, Rb1, and Rd were evaluated and identified as pharmacokinetic markers for indicating rat systemic exposure to Sanqi extract, important for linking Sanqi administration to its medicinal effects.
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The anti-inflammatory activities of Tanshinone IIA, an active component of TCM, are mediated by estrogen receptor activation and inhibition of iNOS
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Acupuncture-related adverse events: a systematic review of the Chinese literature.
TLDR
Many acupuncture-related adverse events, most of them owing to improper technique, have been described in the published Chinese literature and efforts should be made to find effective ways of monitoring and minimizing the risks related to acupuncture.
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Palmitoylation-dependent activation of MC1R prevents melanomagenesis
TLDR
It is shown that pharmacological activation of palmitoylation rescues the defects of Mc1r RHC variants and prevents melanomagenesis, highlighting a central role for MC1R palmitoyslation in pigmentation and protection against melanoma.
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Neuroprotective effects of scutellarin against hypoxic-ischemic-induced cerebral injury via augmentation of antioxidant defense capacity.
TLDR
The results suggest that the preventive and therapeutic potential of scutellarin in cerebral injury patients is, at least in part, ascribed to augmentation of cellular antioxidant defense capacity.
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Cuscuta chinensis Lam.: A systematic review on ethnopharmacology, phytochemistry and pharmacology of an important traditional herbal medicine.
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Plasma and Urinary Tanshinol from Salvia miltiorrhiza (Danshen) Can Be Used as Pharmacokinetic Markers for Cardiotonic Pills, a Cardiovascular Herbal Medicine
TLDR
Plasma and urinary TSL are promising PK markers for cardiotonic pills at the tested dose levels and extensive presystemic hepatic elimination and degradation in the erythrocytes led to extremely low plasma levels and poor dose proportionality.
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Qi-Shen-Yi-Qi Dripping Pills for the Secondary Prevention of Myocardial Infarction: A Randomised Clinical Trial
TLDR
The result suggests that QSYQ has similar effects to aspirin in the secondary prevention of MI, and this trial did not show significant difference of primary and secondary outcomes between aspirin and Q SYQ in patients who have had an MI.
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Targeting the upstream transcriptional activator of PD-L1 as an alternative strategy in melanoma therapy
Programmed cell death ligand 1 (PD-L1) interacts with programmed cell death protein-1 (PD-1) as an immune checkpoint. Reactivating the immune response by inhibiting PD-L1 using therapeutic antibodies…
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