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Polymorphism of the prolactin gene and its association with egg production traits in native Chinese ducks
As a candidate gene related to egg production, prolactin plays a crucial role in the reproduction of birds. In this study, polymorphism of the prolactin gene was screened in six Chinese native duck
Polydatin ameliorates Staphylococcus aureus-induced mastitis in mice via inhibiting TLR2-mediated activation of the p38 MAPK/NF-κB pathway
PD does not exhibit antibacterial activity against S aureus, its therapeutic effects in mouse S a Aureus-induced mastitis depend on its ability to down-regulate pro-inflammatory cytokine levels via inhibiting TLR2-mediated activation of the p38 MAPK/NF-κB signaling pathway.
Endothelin Receptor B2 (EDNRB2) Gene Is Associated with Spot Plumage Pattern in Domestic Ducks (Anas platyrhynchos)
A phylogenetic tree based on amino acid sequences showed that duck EDNRB2 was evolutionary conserved in avian clade and melanocytes are absent in non-pigmented skin tissues of spot ducks.
Non-synonymous SNPs in MC1R gene are associated with the extended black variant in domestic ducks (Anas platyrhynchos).
A sequence characterization of the duck melanocortin 1 receptor (alpha-melanocyte stimulating hormone receptor) gene is performed to analyze the relationship between MC1R polymorphism and the extended black variant in domestic ducks based on the extendedBlack (E) and non-extended black (e(+) ) allele hypothesis of the ducks.
Polydatin reduces Staphylococcus aureus lipoteichoic acid‐induced injury by attenuating reactive oxygen species generation and TLR2‐NFκB signalling
Results have shown that PD could reduce the NF‐κB p65, and IκBα phosphorylation levels increased by LTA, resulting in a decrease in the transcription of pro‐inflammatory factors, such as TNF‐α, IL‐1β and IL‐6, and that PD suppressed LTA‐induced injury by attenuating ROS generation and TLR2‐NFκB signalling.
Mechanism of ESAT-6 membrane interaction and its roles in pathogenesis of Mycobacterium tuberculosis.
IFN-τ Plays an Anti-Inflammatory Role in Staphylococcus aureus-Induced Endometritis in Mice Through the Suppression of NF-κB Pathway and MMP9 Expression.
Findings suggested that IFN-τ plays an anti-inflammatory role in S. aureus-induced endometritis by suppressing NF-κB pathway and MMP9 expression.