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AIMS To determine whether E-selectin deficiency can attenuate brain ischemia in a mouse model of focal cerebral ischemia. METHODS E-selectin was determined in spontaneously hypertensive rats (SHRs) and stroke-prone spontaneously hypertensive rats (SHR-SPs). E-selectin knockout (Es(-/-) ) mice and wild-type control (WT) mice underwent permanent distal(More)
Ten years passed from the study of how open source projects develop compared with commercial projects by Mockus et al. More and more companies have been joining and supporting open source projects. Have they changed the essence of OSS development? Do the hypotheses in the former study still hold? In this paper we replicate Apache study to understand the(More)
Whereas most research on Internetware has focused on new technologies for keeping track of a changing Internet, little attention has been paid to the software development process. A large portion of the software running the Internet is open source software. Open source software is developed both by volunteers and commercial companies, often jointly.(More)
AIM To investigate the effects of allisartan, a new angiotensin II type 1 (AT(1)) receptor antagonist, on blood pressure (BP) and end-organ damage (EOD) in hypertensive rats and dogs. METHODS First, a single dose of allisartan was given intragastrically to evaluate the BP reduction in spontaneously hypertensive rats (SHRs), two kidney-one clip (2K1C)(More)
AIM To reinvestigate the characteristics of reserpine-induced gastric mucosal lesions (GMLs). METHODS The GML-inducing effect of reserpine and the time-course of recovery from reserpine-induced GMLs were examined in Sprague-Dawley (SD) rats. The GML-inducing and blood pressure-decreasing effects of Compound Hypotensive Tablets (CHTs) were investigated in(More)
Previous studies have reported an association between vitamin D receptor (VDR) gene polymorphisms and Parkinson's disease (PD), but the results were controversial. To explore whether VDR gene polymorphisms have an effect on PD risk, we performed this meta-analysis to evaluate the association between three VDR gene polymorphisms (Bsml, Apal, Taql) and PD(More)
<b>Motivation:</b> Open-source projects are often supported by companies, but such involvement often affects the robust contributor inflow needed to sustain the project and sometimes prompts key contributors to leave. To capture user innovation and to maintain quality of software and productivity of teams, these projects need to attract and retain(More)
The NLRP3 inflammasome (NOD-like receptor family, pyrin domain containing 3) is an intracellular protein complex that plays an important role in innate immune sensing. Its activation leads to the maturation of caspase-1 and regulates the cleavage of interleukin (IL)-1β and IL-18. Various studies have shown that activation of the immune system plays a(More)
Controlling complex network is an essential problem in network science and engineering. Recent advances indicate that the controllability of complex network is dependent on the network's topology. Liu and Barabási, et.al speculated that the degree distribution was one of the most important factors affecting controllability for arbitrary complex directed(More)