Xiufang Li

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Polyethylenimine (PEI) has attracted much attention as a DNA condenser, but its toxicity and non-specific targeting limit its potential. To overcome these limitations, Antheraea pernyi silk fibroin (ASF), a natural protein rich in arginyl-glycyl-aspartic acid (RGD) peptides that contains negative surface charges in a neutral aqueous solution, was used to(More)
The development of a novel cationized polymer used as a gene delivery carrier that can conveniently and effectively transfect cells resulting in a stably expressed target gene remains a challenge. Antheraea pernyi silk fibroin (ASF) is a cytocompatible and biodegradable natural polymer, and it possesses Arg-Gly-Asp sequences but a negative charge. In order(More)
MicroRNAs (miRNAs) have been improved to regulate oocyte development in a cell- or stage-specific manner. In this study, we aimed to clarify microRNA-224's (miR-224) role in cumulus cells (CCs), to find out whether a change level of miR-224 in CCs could influence the maturation of oocyte. We found that overexpression of miR-224 of CCs led to the impairment(More)
construction of near double-hole parallel tunnels frequently occurs in city subway evacuation. Studying the dynamical behaviors of the parallel tunnel construction, performing systematic numerical analysis and grasping mutual influences of different factors on the tunnel evacuation and different effects of surface sedimentation has important theoretical(More)
mutual influence of the double-hole tunnel evacuation of urban subways is one of key issues involving the subway construction safety. The asynchronous one-direction evacuation, synchronous one-direction evacuation and opposite evacuation methods are frequently used in double-hole tunnel evacuation. This paper establishes three-dimensional numerical model by(More)
In this paper, several useful inequalities for uncertain variables are proved. A Borel-Cantelli lemma for uncertain measures is obtained and some convergence theorems for continuous uncertain measures are derived. Finally, these theorems are applied to compute the uncertainty distribution of Liu integral. We prove that the uncertain integral of a(More)
Tunneling nanotubes are important membrane channels for cell-to-cell communication. In this study, we investigated the effect of the microenvironment on nanotubular structures by preparing a three-dimensional silk fibroin micropillar structure. In previous reports, tunneling nanotubes were described as stretched membrane channels between interconnected(More)