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Adiponectin plays an important role in the development of hypertension, atherosclerosis, and cardiomyocyte hypertrophy, but very little was known about the influence of serum adiponectin or the adiponectin gene polymorphism on myocardial fibrosis. Our study investigates the influence of the SNP +45 polymorphism of the adiponectin gene and serum levels of(More)
Menstrually related migraine (MRM) is defined as occurring from days-2 to +3 of menstruation in at least 2 out of 3 menstrual cycles, and additionally at other times of the menstrual cycle. MRM is generally longer lasting, more severe, and more difficult to treat compared to non-MRM attacks. MAP0004 is an investigational orally inhaled dihydroergotamine(More)
Oral tablets are the predominant route of administration for the acute treatment of migraine. Gastric Stasis (GS) is commonly associated with migraine, and can significantly alter the rate of intestinal absorption of an oral tablet, leading to inconsistent response to the administered drug. The Tmax of a triptan administered as a tablet can vary from 25-120(More)
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