Xiu-Li Zhang

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The differential expression of extracellular thiol groups by Acidithiobacillus ferrooxidans grown on substrates Fe(2+) and S(0) was investigated by using synchrotron radiation based scanning transmission X-ray microscopy (STXM) imaging and microbeam X-ray fluorescence (μ-XRF) mapping. The extracellular thiol groups (SH) were first alkylated by iodoacetic(More)
Although various microRNAs (miRNAs) regulate immune and inflammatory responses, the function of miRNAs in periodontitis has not been clearly illuminated. In this study, we measured miRNA-146 (miRNA-146a and miRNA-146b-5p) expression and explored its regulatory function in the inflammatory response in human gingival fibroblasts (HGFs). miRNA-146a and(More)
OBJECTIVE To observe the effects of icariin and astragalosid I on the proliferative and alkaline phosphatase (ALP) activity of dog bone marrow stromal cells (BMSCs). METHODS The dog's BMSCs were isolated and cultured in vitro. The 3th generation BMSCs were treated with icariin or astragalosid I at the concentration of 50 ng/ml and compared with BMSCs of(More)
BACKGROUND Tissue-engineering techniques combined with gene therapy have been recently reported to improve osteogenesis. In this study, tissue-engineered bone constructed by human Bone Morphogenetic Protein 4 (hBMP-4) gene-modified bone marrow stromal cells (bMSCs) was explored in an ectopic bone formation model in rabbits. METHODS A pEGFP-hBMP-4(More)
White spot syndrome virus (WSSV) is one of the most virulent pathogens affecting penaeid shrimp, causing high mortality in infected populations. Interactions between virus structural proteins are likely to be important for virus assembly. Many steps of the WSSV assembly and maturation pathway remain unclear. In the present study, the interaction between(More)
Marine-derived fungi have proved to be a promising source of structurally novel and biologically active secondary metabolites that have become interesting and significant resources for drug discovery [1, 2]. Perylene derivatives have been isolated from the marine-derived fungi of the genera of Alternaria and Stemphylium [3, 4]. They are of ten were found to(More)
The brainstem is well recognized as a critical site for integrating descending modulatory systems that both inhibit and facilitate pain at the level of the spinal cord. The cerebrospinal fluid-contacting nucleus (CSF-contacting nucleus) distributes and localizes in the ventral periaqueductal central gray of the brainstem. Although emerging lines of evidence(More)
Porphyromonas gingivalis alters cytokine expression in gingival epithelial cells, stimulating inflammatory responses that may lead to periodontal disease. This study explored the effect of Lactobacillus acidophilus on the specific expressions of the interleukins (ILs) IL1B, IL6, and IL8 induced by the pathogen. Human gingival epithelial cells were(More)
C-Glycosyl quinochalcones are unique components in Carthamus tinctorius L. The reported C-glycosyl quinochalcones have the same quinochalcone skeleton with a hydroxyl group at the 5'-position and a glucose linked to this position with a carbon-carbon bond. In this study, the standard hydroxysafflor yellow A and water-extracted fraction of Carthamus(More)
Chemical investigation of the gorgonian Menella kanisa Grassoff collected from the South China Sea led to the isolation of a new sesquiterpene, menecubebane A (1), together with three known compounds, 8-methoxy-trans-calamenene (2), 8,9-dihydro-linderazulene (3) and (3β)-oleanan-3-ol (4). The structure of 1 was determined by detailed analysis of the(More)