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5‑fluorouracil (5‑FU) is commonly used in the treatment of gastric cancer; however, resistance to this drug occurs under hypoxic conditions. Celecoxib may be used to reverse this resistance. The aim of the present study was to elucidate the inhibitory effects and mechanisms of 5‑FU and celecoxib on the gastric cancer cell line SGC7901 under hypoxic(More)
5-Fluorouracil (5-Fu) is one of the most commonly used drugs to treat gastric cancer; however, drug-resistance in cancer cells reduces the efficacy of 5‐Fu. Celecoxib may be able to reduce resistance to 5‐Fu chemotherapy. The aim of the present study was to investigate the inhibitory effects of a combination of 5‐Fu and celecoxib on implanted gastric cancer(More)
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