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Traditional research modes aim to find cancer-specific single therapeutic target. Recently, emerging evidence suggested that some micro-RNAs (miRNA) can function as oncogenes or tumor suppressors. miRNAs are single-stranded, small noncoding RNA genes that can regulate hundreds of downstream target genes. In this study, we evaluated the miRNA expression(More)
This paper proposes a stylized model that reconciles several seemingly conflicting findings on financial security returns and option prices. The model is based on a pure jump Lévy process, wherein the jump arrival rate obeys a power law dampened by an exponential function. The model allows for different degrees of dampening for positive and negative jumps,(More)
The ATPase NSF (N-ethylmaleimide-sensitive factor) and its SNAP (soluble N-ethylmaleimide-sensitive factor attachment protein) cofactor constitute the ubiquitous enzymatic machinery responsible for recycling of the SNARE (SNAP receptor) membrane fusion machinery. The enzyme uses the energy of ATP hydrolysis to dissociate the constituents of the SNARE(More)
Automatic Speech Emotion Recognition (SER) is a current research topic in the field of Human Computer Interaction (HCI) with wide range of applications. The purpose of speech emotion recognition system is to automatically classify speaker's utterances into five emotional states such as disgust, boredom, sadness, neutral, and happiness. The speech samples(More)
Calcyclin-binding protein (CacyBP)/Siah-1 interacting protein (SIP), a component of ubiquitin-mediated proteolysis, could bind the Skp1-Cul1-F box protein complex. Although CacyBP/SIP was implicated in p53-induced beta-catenin degradation, its exact function was still unknown. Our previous studies showed that CacyBP/SIP could modulate the(More)
Enterovirus 71 (EV71) is a neurotropic virus that causes various clinical manifestations in young children, ranging from asymptomatic to fatal. Different pathotypes of EV71 notably differ in virulence. Several virulence determinants of EV71 have been predicted. However, these reported virulence determinants could not be used to identify the EV71 strains of(More)
Ant colony optimization (ACO) algorithms are often used in robotic path planning; however, the algorithms have two inherent problems. On one hand, the distance elicitation function and transfer function are usually used to improve the ACO algorithms, whereas, the two indexes often fail to balance between algorithm efficiency and optimization effect; On the(More)
Oemona hirta (F.) is a New Zealand native longicorn beetle, whose larvae bore into the wood of branches and stems of living trees and vines, causing serious damage. To explore effective methods for maintaining laboratory colonies and biology of immature stages of this species we evaluated four laboratory rearing methods with both natural and artificial(More)
A Gram-stain negative, rod-shaped, non-motile and pink-pigmented bacterial strain, designated strain HYL7-26T, was isolated from a soil in the Desert Park of Huyang forest located in Xinjiang, China. Phylogenetic analysis based on 16S rRNA gene sequences indicated that strain HYL7-26T belongs to the genus Pontibacter in the family Cytophagaceae. The 16S(More)