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Traditionally, process planning and scheduling for parts were carried out in a sequential way, where scheduling was done after process plans had been generated. Considering the fact that the two functions are usually complementary, it is necessary to integrate them more tightly so that performance of a manufacturing system can be improved greatly. In this(More)
In most cases authors are permitted to post their version of the article (e.g. in Word or Tex form) to their personal website or institutional repository. Authors requiring further information regarding Elsevier's archiving and manuscript policies are encouraged to visit: a b s t r a c t Traditionally, process planning and scheduling were performed(More)
Process planning and scheduling are two of the most important functions in the manufacturing system. Traditionally, process planning and scheduling were regarded as separate tasks performed sequentially, where scheduling was implemented after process plans had been generated. However, their functions are usually complementary. If the two systems can be(More)
Traditionally, process planning and scheduling for parts were carried out in a sequential way, where scheduling was done after process plans had been generated. Considering the fact that the two functions are usually complementary, it is necessary to integrate them more tightly so that performance of a manufacturing system can be improved greatly. In this(More)
BACKGROUND Multiplex digital PCR (dPCR) enables noninvasive and sensitive detection of circulating tumor DNA with performance unachievable by current molecular-detection approaches. Furthermore, picodroplet dPCR facilitates simultaneous screening for multiple mutations from the same sample. METHODS We investigated the utility of multiplex dPCR to screen(More)
Medical procedures in outpatient settings have limited options of managing pain and anxiety pharmacologically. We therefore assessed whether this can be achieved by adjunct self-hypnotic relaxation in a common and particularly anxiety provoking procedure. Two hundred and thirty-six women referred for large core needle breast biopsy to an urban tertiary(More)
The intronic microRNA let-7g controls cell differentiation and proliferation during angiogenesis and oncogenesis. Here, we demonstrate that let-7g regulates granulosa cell (GC) apoptosis and follicular atresia in the pig ovary. Bioinformatics analyses and luciferase reporter assays showed that transforming growth factor-β type 1 receptor (TGFBR1) is a(More)
The hyaluronan synthase 2 (HAS2)-hyaluronic acid (HA)-CD44-Caspase-3 pathway is involved in ovarian granulosa cell (GC) functions in mammals. HAS2 is a key enzyme required for HA synthesis and is the key factor in this pathway. However, the regulation of HAS2 and the HAS2-mediated pathway by microRNAs in GCs is poorly understood. Here, we report that(More)
Systemic blood pressure and cardiac function have long been known to be under the control of central autonomic and hormonal pathways that, in part, use cholinergic neural systems. Recently choline, a precursor and product of acetylcholine metabolism, has been shown to serve as a selective endogenous agonist for the alpha7 subtype of the nicotinic(More)