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Traditionally, process planning and scheduling for parts were carried out in a sequential way, where scheduling was done after process plans had been generated. Considering the fact that the two functions are usually complementary, it is necessary to integrate them more tightly so that performance of a manufacturing system can be improved greatly. In this(More)
BACKGROUND Multiplex digital PCR (dPCR) enables noninvasive and sensitive detection of circulating tumor DNA with performance unachievable by current molecular-detection approaches. Furthermore, picodroplet dPCR facilitates simultaneous screening for multiple mutations from the same sample. METHODS We investigated the utility of multiplex dPCR to screen(More)
Actin cytoskeleton is critical for cell motility and division, both of which are important for angiogenesis. MicroRNAs (miRNA/miR) are emerging as pivotal modulators of vascular development and disease. How miRNAs regulate actin cytoskeleton dynamics in endothelial cells (EC) and neovascularization is still unclear. Here, we report that miR-24 regulates(More)
BACKGROUND Substance dependent individuals (SDIs) consistently show deficits in decision making with biased choices toward immediate rewards, even at the expense of future consequences. However, relatively little evidence has been reported concerning the population of drug abusers who are exclusively addicted to heroin. METHODS The present study tested(More)
In most cases authors are permitted to post their version of the article (e.g. in Word or Tex form) to their personal website or institutional repository. Authors requiring further information regarding Elsevier's archiving and manuscript policies are encouraged to visit: a b s t r a c t Traditionally, process planning and scheduling were performed(More)
Process planning and scheduling are two of the most important functions in the manufacturing system. Traditionally, process planning and scheduling were regarded as separate tasks performed sequentially, where scheduling was implemented after process plans had been generated. However, their functions are usually complementary. If the two systems can be(More)
Traditionally, process planning and scheduling for parts were carried out in a sequential way, where scheduling was done after process plans had been generated. Considering the fact that the two functions are usually complementary, it is necessary to integrate them more tightly so that performance of a manufacturing system can be improved greatly. In this(More)
In a microcosm experiment, the amplified ribosomal DNA restriction analysis was adopted to investigate the Pseudomonas community structure in soils applied with different concentrations (0, 50, 150, and 250 mg/kg) of acetochlor, and an in vitro assay was made to examine the antagonistic activity of isolated Pseudomonas strains acting on soil-borne pathogen(More)
MicroRNAs (miRNAs) modulate complex physiological and pathological processes by repressing expression of multiple components of cellular regulatory networks. Here we demonstrate that miRNAs encoded by the miR-23∼27∼24 gene clusters are enriched in endothelial cells and highly vascularized tissues. Inhibition of miR-23 and miR-27 function by locked nucleic(More)