Xinyong Luan

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OBJECTIVE To investigate the relationship between polymorphism of N-acetyltransferase (NAT2) gene and genetic susceptibility to laryngeal carcinoma. METHODS A case-control study on 62 laryngeal carcinoma patients and 56 controls was conducted. NAT2 alleles were differentiated by polymerase chain reaction-based restriction fragment length polymorphism(More)
Luteolin, a naturally occurring flavonoid, possesses anti-cancer activities against several human cancers, but the exact molecular and biochemical mechanisms of above findings are not very clear, and its activity against head and neck squamous cell carcinoma (HNSCC) is seldom mentioned. In this study, we investigated luteolin against human laryngeal(More)
OBJECTIVE To improve the curative effects of laryngotracheal stenosis. METHOD Seventy patients treated for laryngotracheal stenosis on the different pathologic condition of the larynx and trachea were retrospectively reviewed. Different operative reconstruction methods were used accordingly. RESULT Among 70 patients, 65 (92.9) patients succeed in(More)
OBJECTIVE To assess the quality of life and relevant factors following laryngectomy. METHODS Quality of life was evaluated in 42 laryngeal cancer and hypopharyngeal cancer patients following laryngectomy and in 38 controls. The assessment included General Quality of Life Inventory, University of Washington Quality of Life Head and Neck Questionnaire and a(More)
OBJECTIVE To study the feasibility, surgical technique and results of laryngeal function preservation in surgical treatment for medial wall pyriform sinus cancer. METHODS From 1992 to 1999, 31 patients with medial wall pyriform sinus cancer including stage I 1, II 4, III 14 and IV 12 lesions were treated. Partial resection of pyriform sinus and partial(More)
OBJECTIVE To review the experience of different surgical procedures and corresponding one-stage construction methods for cervical esophageal carcinoma. METHODS 1. Thirty-three patients with cervical esophageal carcinoma were retrospectively reviewed, including 31 males and 2 females. According to UICC 1997 criteria and pathologic findings showing squamous(More)
OBJECTIVE To explore the feasibility and the related surgical techniques of laryngeal function preservation in surgical treatment of posterior hypopharyngeal wall cancer. METHOD Thirty-five cases with posterior hypopharyngeal wall cancer were treated surgically. The methods of removing tumor and repairing surgical defects were depended on the extension of(More)
OBJECTIVE To explore the methods of surgery and evaluate the long-term results of preservative surgery for T3 glottic cancer. METHOD Seventy-five cases with T3 glottic cancer were treated surgically from 1989 to 1999. The lesions were removed entirely, the epiglottis, bi-pedicled myoperichondral flap, platysma myocutaneous flap, sternohyoid myofascial(More)
OBJECTIVE To observe the long-term effects of clinical treatment for laryngeal carcinoma recurrence and cervical metastasis, and discuss the operative therapy method for laryngeal carcinoma recurrence and cervical metastasis. METHOD Retrospective analysis the 70 patients with laryngeal carcinoma recurrence and cervical metastasis who was cured in our(More)
OBJECTIVE To observe the appliance value of uni-pedicled sternohyoid myofascial flap in laryngeal function reconstruction after partial laryngectomy. METHOD Forty patients who underwent partial laryngectomy from 1981 to 1999 were summarized(male 36 cases, female 4 cases). Among them 19 were supraglottic carcinomas (T2N0 6, T2N2 1, T3N0 2, T3N1 1, T3N2 2,(More)