Xinyi Guo

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Retinoblastoma (Rb) is a common childhood intraocular cancer that affects approximately 300 children each year in the United States alone. 2-Methoxyestradiol (2ME), an endogenous metabolite of 17-β-estradiol that dose not bind to nuclear estrogen receptor, exhibits potent apoptotic activity against rapidly growing tumor cells. Here, we report that 2ME(More)
Endothelial cell (EC) survival is critical in the maintenance of endothelial function as well as in the regulation of angiogenesis and vessel integrity since endothelial dysfunction is the initial lesion of atherosclerosis. The goal of this study was to examine the effect of diazoxide, a mitochondrial ATP-sensitive K(+)(mito K(ATP)) channel opener, on aorta(More)
Our objective was to characterize the elasticity of hydrogel formulations intended to mimic physical properties that cells and tissues experience in vivo. Using atomic force microscopy (AFM), we tested a variety of concentrations in a variety of biomaterials, including agarose, alginate, the collagens, fibrin, hyaluronic acid, kerateine, laminin, Matrigel,(More)
We report the fabrication of the La2/3Sr1/3MnO3 (LSMO)/graphene/Co sandwich structures employing single-layer graphene as the interlayer. Appreciable negative spin valve signals were observed from room temperature to 5 K. We find that the devices demonstrate nonlinear current-voltage (I-V) characteristics around room temperature, indicating that the(More)
The whole chloroplast (cp) genome sequence of Idesia polycarpa has been characterized from Illumina pair-end sequencing. The complete cp genome was 157,017 bp in length, containing a large single copy region (LSC) of 84,787 bp and a small single copy region (SSC) of 16,512 bp, which were separated by a pair of 27,859 bp inverted repeat regions (IRs). The(More)
The complete chloroplast genomes from two sister species of Pugionium Gaertn are determined in this study. The genome sizes were 155,002 bp (Pugionium dolabratum) and 154,992 bp (Pugionium cornutum). Both genomes containing a large single copy region of 84 k bp and a small single copy region of 18 k bp, which were separated by a pair of 26,761 bp inverted(More)
As the second most prevalent hematologic malignancy, multiple myeloma (MM) remains incurable and relapses due to intrinsic or acquired drug resistance. Therefore, new therapeutic strategies that target molecular mechanisms responsible for drug resistance are attractive. Interactions of tumor cells with their surrounding microenvironment impact tumor(More)
The complete chloroplast (cp) sequence of the salt cress (Eutrema salsugineum), a plant well-adapted to salt stress, was presented in this study. The circular molecule is 153,407 bp in length and exhibit a typical quadripartite structure containing an 83,894 bp large single copy (LSC) region, a 17,607 bp small single copy (SSC) region, and the two 25,953 bp(More)
Customer service satisfaction has become one of cores of modern service industry competition. An accurate evaluation of customer service satisfaction is a base to improve the service quality. This paper construct the service quality evaluation system of fast food industry based on the customer's point of view, and put forward the questionnaire of service(More)