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An increased risk of HIV-1 associated dementia (HAD) has been observed in patients abusing methamphetamine (METH). Since both HIV viral proteins (gp120, Tat) and METH induce oxidative stress, drug abusing patients are at a greater risk of oxidative stress-induced damage. The objective of this study was to determine if N-acetylcysteine amide (NACA) protects(More)
—Breast cancer is a common form of cancer diagnosed in women. Clustered microcalcifications(MCs) in mammograms is one of the important early sign. Their accurate detection is a key problem in computer aided detection (CDAe). In this paper, a novel approach based on the recently developed machine learning technique-twin support vector machines (TWSVM) to(More)
Oxidative stress plays an important role in neurodegenerative disorders such as Parkinson's disease and Alzheimer's disease. Methamphetamine (METH) is an amphetamine analog that causes degeneration of the dopaminergic system in mammals and subsequent oxidative stress. In our present study, we have used immortalized human brain microvascular endothelial(More)
BACKGROUND Most emerging health threats are of zoonotic origin. For the overwhelming majority, their causative agents are RNA viruses which include but are not limited to HIV, Influenza, SARS, Ebola, Dengue, and Hantavirus. Of increasing importance therefore is a better understanding of global viral diversity to enable better surveillance and prediction of(More)
Modeling and simulating the effects of human factors on landscape change remain as challenges for ecological studies. In this paper, we present a dynamic landscape simulation (DLS) approach to elucidate human-induced landscape changes for a 5104 km 2 study area within the Chicago metropolitan region. The DLS consists of an urban growth simulation submodel(More)
Measles virus is a negative-sense, single-stranded RNA virus within the Mononegavirales order,which includes several human pathogens, including rabies, Ebola, Nipah, and Hendra viruses. The measles virus nucleoprotein consists of a structured N-terminal domain, and of an intrinsically disordered C-terminal domain, N(TAIL) (aa 401-525), which undergoes(More)
—In this paper, a novel algorithm for mammographic images enhancement and denoising based on Multiscale Geometric Analysis (MGA) is proposed. Firstly mammograms are decomposed into different scales and directional subbands using Nonsubsampled Contourlet Transform (NSCT). After modeling the coefficients of each directional subbands using Generalized Gaussian(More)
—In this paper we discuss a new approach for the detection of clustered microcalcifications (MCs) in mammograms. MCs are an important early sign of breast cancer in women. Their accurate detection is a key issue in computer aided detection scheme. To improve the performance of detection, we propose a Bagging and Boosting based twin support vector machine(More)
Color is an indispensible characteristic of food because it makes foods easily recognizable and attractive in our modern society. Numerous food colors have been removed from the national and international lists of “accepted food colors” due to their mutagenic and carcinogenic activities based on a number of toxicity studies that have been conducted since(More)