Xinrong Zhou

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CONTEXT Betatrophin has recently attracted increasing interests as a potential β-cell regenerative therapy in diabetes. However, differences in betatrophin profiles in patients with type 2 diabetes mellitus (T2DM) remain unclear. OBJECTIVE The objective of the study was to examine circulating betatrophin levels in subjects with different glucose tolerance(More)
BACKGROUND To directly compare traditional lipid ratios (total cholesterol [TC]/high density lipoprotein cholesterol [HDL-C], non-HDL-C/HDL-C, low density lipoprotein cholesterol [LDL-C]/HDL-C, and triglycerides [TG]/HDL-C), apolipoprotein B (apoB)/apolipoprotein A-I (apoA-I) ratio, visceral adiposity index (VAI), lipid accumulation product (LAP), and the(More)
Gastric bypass surgery produces clear antidiabetic effects in a substantial proportion of morbidly obese patients. In view of the recent trend away from 'bariatric' surgery and toward 'metabolic' surgery, it is important to elucidate the enhancing effect of bypass surgery on pancreatic β-cell mass, which is related to diabetes remission in non-obese(More)
Peer-to-peer (P2P) networks and mobile ad hoc networks (MANET) share some key characteristics: self-organization and decentralization, and both need to solve the same fundamental problem: connectivity. We motivate a study for the convergence of the two overlay network technologies and sketch an evolving architecture towards integrating the two technologies(More)
We developed a procedure for identifying transcriptional Master Regulators (MRs) related to special biological phenomena, such as diseases, in conjunction with network screening and inference. Network screening is a system for detecting activated transcriptional regulatory networks under particular conditions, based on the estimation of graph structure(More)
We estimated the key molecules related to Type 2 diabetes mellitus (T2DM) in adipose, liver, and muscle tissues, from nonobese diabetic Goto-Kakizaki (GK) rats and their Wistar controls, by computationally analyzing the expression profiles in open source data. With the aid of information from previous reports, Rev-erbα in adipose tissue emerged as one of(More)
OBJECTIVE Sex differences in the association of HbA1c and cardiovascular disease (CVD) risk remain controversial. We examined CVD risk profile in both HbA1c-defined diabetic and nondiabetic men and women. METHODS We conducted a cross-sectional analysis of 7139 Chinese adults using data from the China Health and Nutrition Survey 2009. RESULTS(More)