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CONTEXT Betatrophin has recently attracted increasing interests as a potential β-cell regenerative therapy in diabetes. However, differences in betatrophin profiles in patients with type 2 diabetes mellitus (T2DM) remain unclear. OBJECTIVE The objective of the study was to examine circulating betatrophin levels in subjects with different glucose tolerance(More)
BACKGROUND To directly compare traditional lipid ratios (total cholesterol [TC]/high density lipoprotein cholesterol [HDL-C], non-HDL-C/HDL-C, low density lipoprotein cholesterol [LDL-C]/HDL-C, and triglycerides [TG]/HDL-C), apolipoprotein B (apoB)/apolipoprotein A-I (apoA-I) ratio, visceral adiposity index (VAI), lipid accumulation product (LAP), and the(More)
Peer-to-peer (P2P) networks and mobile ad hoc networks (MANET) share some key characteristics: self-organization and decentralization, and both need to solve the same fundamental problem: connectivity. We motivate a study for the convergence of the two overlay network technologies and sketch an evolving architecture towards integrating the two technologies(More)
We developed a procedure for identifying transcriptional Master Regulators (MRs) related to special biological phenomena, such as diseases, in conjunction with network screening and inference. Network screening is a system for detecting activated transcriptional regulatory networks under particular conditions, based on the estimation of graph structure(More)
BACKGROUND Hyperglycemia is common and hard to control in surgical patients with diabetes. We retrospectively investigated short-term effects of continuous subcutaneous insulin infusion (CSII) in perioperative patients with diabetes. PATIENTS AND METHODS Perioperative patients with diabetes discharged between January 1, 2006 and January 1, 2012 were(More)
A lot of networks today are behind firewalls. In peer-to-peer networking, firewall-protected peers may have to communicate with peers outside the firewall. This paper shows how to design peer-to-peer systems to work with different kinds of firewalls within the object-oriented action systems framework by combining formal and informal methods. We present our(More)
OBJECTIVE There has been conflicting evidence regarding the role of single lipid species in the pathogenesis of nonalcoholic fatty liver disease (NAFLD). We aimed to explore the associations between dyslipidemia phenotypes (combinations of lipid parameters) and the risk of NAFLD. METHODS We conducted a cross-sectional analysis using a cohort of 9560(More)