Xinhua Zhu

Learn More
BACKGROUND The tumor suppressor TP53 and its negative regulator MDM2 play crucial roles in carcinogenesis. Previous case-control studies also revealed TP53 72Arg>Pro and MDM2 309T>G polymorphisms contribute to the risk of common cancers. However, the relationship between these two functional polymorphisms and nasopharyngeal carcinoma (NPC) susceptibility(More)
Agent-based workflow has been proven its potential in overcoming issues in traditional workflow-based systems, such as decentralization, organizational issues, etc. The existing data mining tools provide workflow metaphor for data mining process visualization, audition and monitoring; these are particularly useful for distributed environments. In(More)
Performance and user-friendliness are big challenges for data mining tools. In this demo, we introduced an agent-based distributed data mining platform. User can use it to manage and share the data mining-related resources conveniently. An example is introduced to illustrate how the whole platform works in distributed environment. It has satisfactory(More)
Charr populations are particularly susceptible to change, either from the application of harvest or environmental conditions such as climate variation. As an alternative to conventional fishery analysis, we analyze the sustainability and viability of selected North American charr stocks using a number of approaches. We compare several methods for data(More)
The present study aimed to use RNA interference (RNAi) to silence chemokine receptor 3 (CCR3) and observe the effects on eosinophils (EOS) in mice with allergic rhinitis (AR). CCR3 small interfering RNA (siRNA) lentiviral vectors were transduced into purified EOS cells cultured in vitro. Reverse transcription-polymerase chain reaction (RT-PCR) and western(More)
The shortest path between two concepts in a taxonomic ontology is commonly used to represent the semantic distance between concepts in the edge-based semantic similarity measures. In the past, the edge counting is considered to be the default method for the path computation, which is simple, intuitive and has low computational complexity. However, a large(More)