• Publications
  • Influence
Inulin-type fructan improves diabetic phenotype and gut microbiota profiles in rats
Background & Aims Accumulating research has addressed the linkage between the changes to gut microbiota structure and type 2 diabetes (T2D). Inulin is one type of soluble dietary fiber that canExpand
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DNA methylation: the pivotal interaction between early-life nutrition and glucose metabolism in later life.
Traditionally, it has been widely acknowledged that genes together with adult lifestyle factors determine the risk of developing some metabolic diseases such as insulin resistance, obesity andExpand
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Maternal High-Fat Diet Modulates Hepatic Glucose, Lipid Homeostasis and Gene Expression in the PPAR Pathway in the Early Life of Offspring
Maternal dietary modifications determine the susceptibility to metabolic diseases in adult life. However, whether maternal high-fat feeding can modulate glucose and lipid metabolism in the early lifeExpand
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Change of Body Composition and Adipokines and Their Relationship with Insulin Resistance across Pubertal Development in Obese and Nonobese Chinese Children: The BCAMS Study
  • L. Xu, M. Li, +5 authors J. Mi
  • Medicine
  • International journal of endocrinology
  • 11 December 2012
A transient increase in insulin resistance (IR) is a component of puberty. We investigated the impact of body composition and adipokines on IR during puberty in Chinese children. This study includedExpand
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Vildagliptin increases butyrate-producing bacteria in the gut of diabetic rats
Emerging evidence supports a key role for the gut microbiota in metabolic diseases, including type 2 diabetes (T2D) and obesity. The dipeptidyl peptidase-4 inhibitor vildagliptin is highlyExpand
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Association Between Glycosylated Hemoglobin Level and Cardiovascular Outcomes in Diabetic Patients After Percutaneous Coronary Intervention
AbstractGlycosylated hemoglobin (HbA1c) is a critical measure of glycemic control, which may be a reliable predictor of complications after percutaneous coronary intervention (PCI). This systematicExpand
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The Placental Microbiome Varies in Association with Low Birth Weight in Full-Term Neonates
Substantial evidence indicated that low birth weight was an independent risk factor for obesity, impaired glucose regulation, and diabetes later in life. However, investigations into the associationExpand
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Berberine Moderates Glucose and Lipid Metabolism through Multipathway Mechanism
Berberine is known to improve glucose and lipid metabolism disorders, but the mechanism is still under investigation. In this paper, we explored the effects of berberine on the weight, glucoseExpand
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Evidence of a Relationship between Infant Birth Weight and Later Diabetes Mellitus and Impaired Glucose Regulation in a Chinese Population
Objective: To determine the influence of birth weight, a marker of fetal growth, on the development of later impaired glucose metabolism throughout the life-span of people living in China. ResearchExpand
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Berberine moderates glucose metabolism through the GnRH-GLP-1 and MAPK pathways in the intestine
BackgroundBerberine is known to improve glucose and lipid metabolism disorders, but it poorly absorbed into the blood stream from the gut. Therefore, the exact underlying mechanism for berberine isExpand
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