Xingye Lei

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BACKGROUND The rates of molecular evolution for protein-coding genes depend on the stringency of functional or structural constraints. The Ka/Ks ratio has been commonly used as an indicator of selective constraints and is typically calculated from interspecies alignments. Recent accumulation of single nucleotide polymorphism (SNP) data has enabled the(More)
During cell division, cells form the microtubule-based mitotic spindle, a highly specialized and dynamic structure that mediates proper chromosome transmission to daughter cells. Cancer cells can show perturbed mitotic spindles and an approach in cancer treatment has been to trigger cell killing by targeting microtubule dynamics or spindle assembly. To(More)
Data fusion (or information integration) from different sources is required for many technical fields, including epidemiology, medicine, biology, business, and military applications such as intelligence. Data fusion may involve integration of spectral content with imaging, text, and many other observations or with sensor data. Therefore, any software system(More)
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